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Chronic obstructive pulmonary disease (COPD) and erectile dysfunction (ED): Results of the BRED observational study

Stefano Lauretti, Vittorio Cardaci, Francesco Barrese, Luigino Calzetta
  • Stefano Lauretti
    Center of Sexual Medicine and Urological Rehabilitation. Day Surgery Unit, PSCR S. Caterina della Rosa, ASL Roma C, Roma, Italy |
  • Vittorio Cardaci
    Physiopathology and Respiratory Rehabilitation Unit IRCSS San Raffaele Pisana, Rome, Italy
  • Francesco Barrese
    Unit of Urology, Fabia Mater, Rome, Consultant in Urology IRCSS San Raffaele, Rome, Italy
  • Luigino Calzetta
    Laboratory of Systems Approaches, IRCSS San Raffaele Pisana, Rome, Italy


Most patients with chronic obstructive pulmonary disease (COPD) share many risk factors and similar aetiological agents with erectile dysfunction (ED). Both conditions also cause serious interference with quality of life and sexual relationships. In general, ageing and chronic illness decrease sexual interest, sexual function, and testosterone levels. This observational study included 66 male patients referred to our centre with different grades of COPD. We studied the different correlations between COPD and ED. The data collected from each patient regarded the following features: demographic and social condition; smoking status; clinical status; spirometric measurements. In this group, COPD was diagnosed in 78.8% and ED was present in 83.3% with increased severity in presence of LUTS and nicotinism.


Chronic obstructive pulmonary disease (COPD); Erectile dysfunction; Endothelial dysfunction, Chronic inflammation.

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Submitted: 2015-08-18 11:22:43
Published: 2016-10-05 16:52:24
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Copyright (c) 2016 Stefano Lauretti, Vittorio Cardaci, Francesco Barrese, Luigino Calzetta

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