https://doi.org/10.4081/hls.2024.12402
Analysis of the link between stress and cancer: implications for patient support
Submitted: 19 February 2024
Accepted: 9 April 2024
Published: 27 May 2024
Accepted: 9 April 2024
Abstract Views: 610
PDF: 137
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
In a world where oncological diseases remain a serious problem for many people, the study of stress management and the provision of psychological support to prevent and treat oncological diseases are becoming increasingly relevant. The purpose of the article is to identify stress mechanisms that affect the human body and provoke the development of cancer.Additionally, it seeks to investigate the global scope of the stress-cancer connection. The methods used in the study include generalisation, analysis, synthesis, and systematisation. The study found that chronic stress can affect the immune system, neurological activity, and other processes contributing to cancer development. In addition, the study has managed to shed light on the mechanisms of stress impact on oncology, including oxidative stress and replication stress, as stimuli that threaten the normal functioning of the human body. A support program for patients with oncological diseases was developed, which included assessment, psychoeducation, methods of stress reduction, and post-treatment support for patients with oncological diseases or those predisposed to them. The study found that the introduction of stress reduction programs for cancer patients is an important step in improving their well-being and treatment outcomes.
Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer J Clin 2021;71:209-49.
DOI: https://doi.org/10.3322/caac.21660
Binnur Dönmez B. WHO warns global cancer burden growing, with 77% spike in cases expected by 2050. 2024. Available from: https://www.aa.com.tr/en/health/who-warns-global-cancer-burden-growing-with-77-spike-in-cases-expected-by-2050/3125409.
Romash I, Neyko V, Romash I, et al. Post-traumatic stress disorder as a nosological unit: difficulties of the past and challenges of the future. Scientific Studios on Social and Political Psychology. 2022;50:53.
DOI: https://doi.org/10.33120/sssppj.vi50(53).596
Sathishkumar K, Chaturvedi M, Das P, et al. Cancer incidence estimates for 2022 & projection for 2025: result from National Cancer Registry Programme, India. Indian J Med Res. 2022;156:598-607.
DOI: https://doi.org/10.4103/ijmr.ijmr_1821_22
Serhet I. “Internal picture” of the disease and its influence on psychological adaptation to stress during cancer. In: Virtual Man: New Horizons 2020;(pp. 75-8). CPM “ASF”; Montreal, Canada.
Hirna HA, Maltsev DV, Natrus LV, et al. Study of the immunomodulating influence of preparation alpha/beta-defensins on chemo/radiotherapy of patients with oral and oropharyngeal cancer. Fiziologichnyi Zh. 2021;67:86-96.
DOI: https://doi.org/10.15407/fz67.04.086
Makarova OP, Chervonyi PD. The essence of stress and its effect on the human body in extreme conditions. Habitus 2023;46:222-6.
DOI: https://doi.org/10.32782/2663-5208.2023.46.36
Miaskowski C, Paul S, Snowberg K, et al. Stress and symptom burden in oncology patients during the COVID-19 pandemic. J Pain Symptom Manage 2020;60:25-34.
DOI: https://doi.org/10.1016/j.jpainsymman.2020.08.037
Yan J, Chen Y, Luo M, et al. Chronic stress in solid tumor development: From mechanisms to interventions. J Biomed Sci. 2023;30:8.
DOI: https://doi.org/10.1186/s12929-023-00903-9
Lempesis IG, Georgakopoulou VE, Papalexis P, et al. Role of stress in the pathogenesis of cancer (Review). Int J Oncol 2023;63:124.
DOI: https://doi.org/10.3892/ijo.2023.5572
Petrinović SV, Milošević MS, Marković D, et al. Interplay between stress and cancer – A focus on inflammation. Front Physiol 2023;14;1119095.
DOI: https://doi.org/10.3389/fphys.2023.1119095
Tausk F. Psychoneuro-oncology: How chronic stress grows cancer. Clinic Dermatol 2023;41:95-104.
DOI: https://doi.org/10.1016/j.clindermatol.2023.03.008
Dai S, Mo Y, Wang Y, et al. Chronic stress promotes cancer development. Front Oncol. 2020;10:1492.
DOI: https://doi.org/10.3389/fonc.2020.01492
Boichuk OH, Dorofeieva US, Kolomiichenko TV. Hormonal and genetic causes of poor response to controlled ovarian stimulation in women of late reproductive age. Reprod. Endocrinol. 2022;66:62-7.
DOI: https://doi.org/10.18370/2309-4117.2022.66.62-67
Messina A, McCormick LM, Paradiso S. Wernicke-Korsakoff Syndrome and dementia. In: Diet and nutrition in dementia and cognitive decline 2015;(pp. 167-176). Elsevier; Amsterdam, The Netherlands.
DOI: https://doi.org/10.1016/B978-0-12-407824-6.00016-1
Mashudi S, Sansuwito TB, Purwaningroom DL, et al. Occupational balance improves subjective health and quality of life family with mental health disorders. J Intel Disability – Diagn Treat. 2022;10:232-7.
DOI: https://doi.org/10.6000/2292-2598.2022.10.05.4
Langford D, Eaton L, Kober K, et al. A high stress profile is associated with severe pain in oncology patients receiving chemotherapy. Euro J Oncol Nurs 2022;58:102135.
DOI: https://doi.org/10.1016/j.ejon.2022.102135
Maslak K, Favara-Scacco C, Barchitta M, et al. General anesthesia, conscious sedation, or nothing: Decision-making by children during painful procedures. Pediatr Blood Cancer. 2019;66:e27600
DOI: https://doi.org/10.1002/pbc.27600
Duzhych NV, Yeher OY, Synenko MY, et al. Influence of emotional intelligence on the nurse efficiency. Bulletin of Medical and Biological Research. 2023;15:38-43.
Taylor S, Harley C, Campbell L, et al. Discussion of emotional and social impact of cancer during outpatient oncology consultations. Psycho‐Oncol 2011;20:242-51.
DOI: https://doi.org/10.1002/pon.1730
Salyha N. Regulation of oxidative stress and lipid peroxidation induced by epinephrine: the corrective role of L-Glutamic acid. International Journal of Medicine and Medical Research. 2023;9:32-8.
DOI: https://doi.org/10.61751/ijmmr.2413-6077.2023.1.32
Ilderbayev O, Okassova A, Rakhyzhanova S, et al. The levels of oxidative stress in a combination of stress factors. J Med Life. 2022;:927-31.
DOI: https://doi.org/10.25122/jml-2021-0060
Druzhyna M, Domina E, Makovetska L. Metabolites of oxidative stress as predictors of the radiation and carcinogenic risks. Oncol 2019;21:170-5.
DOI: https://doi.org/10.32471/oncology.2663-7928.t-21-2-2019-g.7457
Gaillard H, García-Muse T, Aguilera A. Replication stress and cancer. Nat Rev Cancer 2015;15:276-89.
DOI: https://doi.org/10.1038/nrc3916
Kruk J, Aboul-Enein B, Bernstein J, Gronostaj M. Psychological stress and cellular aging in cancer: A meta-analysis. Oxid Med Cell Longevity 2019;2019:1270397.
DOI: https://doi.org/10.1155/2019/1270397
Gold J, Douglas M, Thomas M, et al. The relationship between posttraumatic stress disorder, mood states, functional status, and quality of life in oncology outpatients. J Pain Symptom Manage 2012;44:520-31.
DOI: https://doi.org/10.1016/j.jpainsymman.2011.10.014
Khupavtseva N. The impact of stress on the human body and ways to overcome it. Psych Real Prosp 2016;7:224-8.
Liu Y, Tian S, Ning B, Huang T, Li Y, Wei Y. Stress and cancer: The mechanisms of immune dysregulation and management. Front Immunol 2022;13:1032294.
DOI: https://doi.org/10.3389/fimmu.2022.1032294
Spytska L. The most common mental disorders in young people and middle-aged people in the modern world. Sci Bull Mukachevo State Univ. Ser Pedag Psychol 2023;9:9-17.
DOI: https://doi.org/10.52534/msu-pp4.2023.09
Abate M, Citro M, Caputo M, Pisanti S, Martinelli R. Psychological stress and cancer: new evidence of an increasingly strong link. Transl Med UniSa 2020;23:53-7.
DOI: https://doi.org/10.37825/2239-9747.1010
Hoffman M, Lent R, Raque-Bogdan T. Social cognitive perspective on coping with cancer: Theory, research, and intervention. Counsel Psycho 2013;41:240-67.
DOI: https://doi.org/10.1177/0011000012461378
Finset A, Heyn L, Ruland C. Patterns in clinicians’ responses to patient emotion in cancer care. Patient Educ Counsel 2013;93:80-5.
DOI: https://doi.org/10.1016/j.pec.2013.04.023
Singer S, Krauß O, Keszte J, et al. Predictors of emotional distress in patients with head and neck cancer. Head Neck 2012;34:180-7.
DOI: https://doi.org/10.1002/hed.21702
Hayes J, Dinkova-Kostova A, Tew K. Oxidative stress in cancer. Cancer Cell 2020;38:167-97.
DOI: https://doi.org/10.1016/j.ccell.2020.06.001
Eckerling A, Ricon-Becker I, Sorski L, et al. Stress and cancer: mechanisms, significance and future directions. Nat Rev Cancer 2021;21:767-85.
DOI: https://doi.org/10.1038/s41568-021-00395-5
Coyne J, Ranchor A, Palmer S. Meta-analysis of stress-related factors in cancer. Nat Rev Clinic Oncol 2010;7:1-2.
DOI: https://doi.org/10.1038/ncponc1134-c1
Ebstein A, Joseph S, Hernandez M. Psychological stress and pancreatic cancer patients: A qualitative systematic review protocol. JBI Evidence Synth 2020;18:576-82.
DOI: https://doi.org/10.11124/JBISRIR-D-18-00006
Messina A, Fogliani AM. Valproate in conversion disorder: A case report. Case Rep Med. 2010;2010:205702.
DOI: https://doi.org/10.1155/2010/205702
Sosa V, Moliné T, Somoza R, et al. Oxidative stress and cancer: An overview. Ageing Res Rev 2013;12:376-90.
DOI: https://doi.org/10.1016/j.arr.2012.10.004
How to Cite
Spytska, L. (2024). Analysis of the link between stress and cancer: implications for patient support. Healthcare in Low-Resource Settings. https://doi.org/10.4081/hls.2024.12402
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