Maternal knowledge and prescribing practices of antibiotics for childhood infections: a cross-sectional survey in Jordan

Submitted: 9 August 2023
Accepted: 3 November 2023
Published: 10 November 2023
Abstract Views: 345
PDF: 124
HTML: 4
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

This article aims to assess the knowledge and practices of Jordanian mothers regarding antibiotic consumption by their children. A questionnaire was distributed to mothers during hospital visits in February-May 2020. Questions were on socio-demographics; knowledge of antibiotic indications/complications; and prescribing practices. A total of 1926 mothers participated. Most mothers were aware that antibiotics are not indicated for viral infections (72.0%), and that abuse leads to complications like antibiotic resistance (82.1%). However, their knowledge regarding antibiotic complications was not satisfactory particularly complications of obesity (11.7%), caries (29.9%), and allergy (43.4%). The most important clinical indications for antibiotics were perceived to be otitis media (89.8%), and sore throat (44.4%). A proportion of 21.7% admitted self-prescribing, significantly among families of ≤2 children, and poor antibiotic knowledge (p<0.01). Lower antibiotic knowledge scores were impacted mostly by grandparents who self-prescribe antibiotics (p<0.01). Jordanian mothers show satisfactory knowledge of pediatric antibiotic consumption, however, their knowledge of complications is not sufficient. Antibiotic self-prescribing is identified mainly in families with lower income and less antibiotic knowledge, therefore these families should be identified and targeted in antibiotic awareness campaigns.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Nyquist AC, Gonzales R, Steiner JF, et al. Antibiotic prescribing for children with colds, upper respiratory tract infections, and bronchitis. Respir Care 1998;279:875-7. DOI: https://doi.org/10.1001/jama.279.11.875
Ababneh MA, Al-Azzam SI, Ababneh R, et al. Antibiotic prescribing for acute respiratory infections in children in Jordan. Int Health 2017;9:124-130. DOI: https://doi.org/10.1093/inthealth/ihx003
Moore AM, Patel S, Forsberg KJ, et al. Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genes. PLoS One 2013;8:e78822. DOI: https://doi.org/10.1371/journal.pone.0078822
Korpela K, Salonen A, Virta LJ, et al. Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children. Nat Commun 2016;7:10410. DOI: https://doi.org/10.1038/ncomms10410
Al Ryalat N, Ryalat S, Al-Abdalla M, et al. Women in Maxillofacial Surgery and Otolaryngology; Career Obstacles and Success Factors. J Craniofac Surg 2021;32:874-877 DOI: https://doi.org/10.1097/SCS.0000000000007132
Al-Niemat SI, Aljbouri TM, Goussous LS, et al. Antibiotic prescribing patterns in outpatient emergency clinics at Queen Rania Al Abdullah II Children’s Hospital, Jordan, 2013. Oman Med J 2014;29:250-4. DOI: https://doi.org/10.5001/omj.2014.67
Dar-Odeh N, Al-Abdalla M, Al-Shayab MH, et al. Antibiotics for pediatric dental patients in Jordan; knowledge and attitudes of dentists. Int Arab J Antimicrob Agents, 2013;3:4.
Al-Shatnawi SF, Al-Hosban SY, Altawalbeh SM, et al. Antibiotic prescribing patterns for childhood infections in ambulatory settings in Jordan. Int J Clin Pract 2021;75:e14740 DOI: https://doi.org/10.1111/ijcp.14740
Lahham A. Multicenter study of pneumococcal carriage in children 2 to 4 years of age in the winter seasons of 2017-2019 in Irbid and Madaba governorates of Jordan. PLoS One 2020;15:e0237247. DOI: https://doi.org/10.1371/journal.pone.0237247
Dar-Odeh NS, Othman BM, Bahabri RH, et al. Antibiotic self-medication for oral conditions: Characteristics and associated factors. Pesqui Bras Odontopediatria Clin Integr 2018;18:3890. DOI: https://doi.org/10.4034/PBOCI.2018.181.27
Yu M, Zhao G, Stålsby Lundborg C, et al. Knowledge, attitudes, and practices of parents in rural China on the use of antibiotics in children: A cross-sectional study. BMC Infect Dis 2014;14:112. DOI: https://doi.org/10.1186/1471-2334-14-112
Jordan News. 56% of students in Jordanian universities are women. https://www.jordannews.jo/Section-109/News/56-of-students-in-Jordanian-universities-are-women-18548. Accessed June 4 2023
Alam S, Mushtaq M. Antibiotic associated diarrhea in children. Indian Pediatr 2009;46:491-6.
Kumar P. Pharmacology of Specific Drug Groups: Antibiotic Therapy. In Dowd FJ, Johnson BS, Mariotti AJ (eds.), Pharmacology and Therapeutics for Dentistry, 7th Ed. 2017; pp. 457–487. DOI: https://doi.org/10.1016/B978-0-323-39307-2.00033-3
Droste JH, Wieringa MH, Weyler JJ, et al. Does the use of antibiotics in early childhood increase the risk of asthma and allergic disease? Clin Exp Allergy 2000;30:1547-53. DOI: https://doi.org/10.1046/j.1365-2222.2000.00939.x
Pitter G, Ludvigsson JF, Romor P, et al. Antibiotic exposure in the first year of life and later treated asthma, a population based birth cohort study of 143,000 children. Eur J Epidemiol 2016;31:85-94; DOI: https://doi.org/10.1007/s10654-015-0038-1
Bentouhami H, Bungwa MK, Casas L, et al. Asthma occurrence in children and early life systemic antibiotic use: an incidence density study. Allergy Asthma Clin Immunol 2023;19:18. DOI: https://doi.org/10.1186/s13223-023-00773-8
Alaki SM, Burt BA, Garetz SL. The association between antibiotics usage in early childhood and early childhood caries. Pediatr Dent 2009;31:31-7.
Meng X, Zhu Y, Di H, et al. Dose-response association of early-life antibiotic exposure and subsequent overweight or obesity in children: A meta-analysis of prospective studies. Obes Rev 2021;22:e13321. DOI: https://doi.org/10.1111/obr.13321
Yallapragada SG, Nash CB, Robinson DT. Early-Life Exposure to Antibiotics, Alterations in the Intestinal Microbiome, and Risk of Metabolic Disease in Children and Adults. Pediatr Ann 2015; 44:e265-9. DOI: https://doi.org/10.3928/00904481-20151112-09
Subih HS, Abu-Shquier Y, Bawadi H, et al. Assessment of body weight, maternal dietary knowledge and lifestyle practices among children and adolescents in north Jordan. Publc Health Nutr 2018;21:2803-2810. DOI: https://doi.org/10.1017/S1368980018001489
Hashem D, Abu Hammad OA, Farran J, et al. Oral health practice of primary school children in the region of Madinah, Saudi Arabia: A cross-sectional study. J Int Oral Health 2021;13:449-55.
Hong L, Levy SM, Warren JJ, et al. Association of amoxicillin use during early childhood with developmental tooth enamel defects. Arch Pediatr Adolesc Med 2005;159:943-8. DOI: https://doi.org/10.1001/archpedi.159.10.943
Kim SY, Chang YJ, Cho HM, et al. Non-steroidal anti-inflammatory drugs for the common cold. Cochrane Database Syst Rev 2015;2015:CD006362. DOI: https://doi.org/10.1002/14651858.CD006362.pub4
Díaz-Lago M, Blanco F, Matute H. Expensive seems better: The price of a non-effective drug modulates its perceived efficacy. Cogn Research 2023;8:8. DOI: https://doi.org/10.1186/s41235-023-00463-4
Burki TK. Development of new antibacterial agents: a sense of urgency needed. Lancet Respir Med 2021;9:e54. DOI: https://doi.org/10.1016/S2213-2600(21)00230-7
Ramadan AM, Rikaby OAA, Abu-Hammad OA, et al. Knowledge and Attitudes Towards Antibiotic Prescribing Among Dentists in Sudan. Pesqui Bras Odontopediatria Clín Integr 2019;19:e4430. DOI: https://doi.org/10.4034/PBOCI.2019.191.17
Bert F, Previti C, Calabrese F, et al. Antibiotics Self Medication among Children: A Systematic Review. Antibiotics (Basel) 2022;11:1583. DOI: https://doi.org/10.3390/antibiotics11111583
Bi B, Qin J, Zhang L, et al. Systematic Review and Meta-Analysis of Factors Influencing Self-Medication in Children. Inquiry 2023;60:469580231159744. DOI: https://doi.org/10.1177/00469580231159744
Ho YL, Mahirah D, Ho CZ, et al. The role of the family in health promotion: a scoping review of models and mechanisms. Health Promot Int 2022;37:daac119. DOI: https://doi.org/10.1093/heapro/daac119

How to Cite

Abdeljawad, R., Abu-Hammad, O., Dar-Odeh, O., Alkouz, F., Abdeljawad, R., Abu-Hammad, A., Abdeljawad, R., & Dar-Odeh, N. (2023). Maternal knowledge and prescribing practices of antibiotics for childhood infections: a cross-sectional survey in Jordan. Healthcare in Low-Resource Settings, 11(1). https://doi.org/10.4081/hls.2023.11647