https://doi.org/10.4081/hls.2023.11548

Antioxidation and anti-inflammatory activities of blended essential oil

Vol. 11 No. 1 (2023)
Submitted: 27 June 2023
Accepted: 23 August 2023
Published: 11 September 2023
Antioxidant, anti-inflammation, essential oil, holistic medicine
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Authors

Suriya Chaiwong
https://orcid.org/0000-0001-9498-1759
Faculty of Integrative Medicine, Rajamangala Univesity of Technology Thanyaburi Prathumthani, Thailand.
Kunthasaya Akkarasiritharattana
Faculty of Integrative Medicine, Rajamangala Univesity of Technology Thanyaburi Prathumthani, Thailand.
Khamjira Jarmkom
Faculty of Integrative Medicine, Rajamangala Univesity of Technology Thanyaburi Prathumthani, Thailand.
Punyanut Amorndoljai
punyanut_a@rmutt.ac.th
https://orcid.org/0009-0004-7097-190X
Faculty of Integrative Medicine, Rajamangala Univesity of Technology Thanyaburi Prathumthani, Thailand.

The mixtures of essential oils are increasing popularly in holistic medicine. The different ratios of oil components in the preparation can result in different health benefits. Therefore, this study aimed to develop a mixture of essential oil formulation having promising bioactivities for pharmaceutical and cosmetic applications. The five popular essential oils including vetiver oil, lavender oil, eucalyptus oil, lemongrass oil, and phlai oil were selected for blended formulation. The selected oils were mixed in a suitable ratio and their antioxidant and anti-inflammatory activities were evaluated using 2,2-Diphenyl-1-picrylhydrazyl radical scavenging and nitric oxide (NO) radical scavenging, respectively. The prepared blended essential oil formulation had clear yellow-pale color and good smell. The blended oil showed good antioxidative activity by acting as a hydrogen donator. However, the blended oil presents mild anti-inflammatory activity via NO quenching action. The results of this study exposed that the developed blended essential oil formulation has promising properties to be used as a natural antioxidant as well as an anti-inflammatory agent in cosmetic and pharmaceutical applications.

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Citations

Crossref
Scopus
Google Scholar
Europe PMC
Guzik T, Korbut R, Adamek-Guzik T. Nitric oxide and superoxide in inflammation. J Physiol Pharmacol 2003;54:469-87.
Rawat A, Rawat M, Prakash OM, et al. Comparative study on eucalyptol and camphor rich essential oils from rhizomes of Hedychium spicatum Sm. and their pharmacological, antioxidant, and antifungal activities. Anais da Academia Brasileira de Ciências, 2022;94. DOI: https://doi.org/10.1590/0001-3765202220210932
Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994;298:249-58. DOI: https://doi.org/10.1042/bj2980249
Mittal M, Siddiqui MR, Tran K, et al. Reactive oxygen species in inflammation and tissue injury. Antiox Redox Signal 2014;20:1126-67. DOI: https://doi.org/10.1089/ars.2012.5149
Sadgrove NJ, Padilla-González GF, Phumthum M. Fundamental chemistry of essential oils and volatile organic compounds, methods of analysis and authentication. Plants 2022;11:789. DOI: https://doi.org/10.3390/plants11060789
Ni ZJ, Wang X, Shen Y, et al. Recent updates on the chemistry, bioactivities, mode of action, and industrial applications of plant essential oils. Trends Food Sci Technol 2021;110:78-89. DOI: https://doi.org/10.1016/j.tifs.2021.01.070
Turek C, Stintzing FC. Stability of essential oil: a review. Compr Rev Food Sci Food Saf 2013;12:40-53. DOI: https://doi.org/10.1111/1541-4337.12006
Horvathova E, Navarova J, Galova E, et al. Assessment of antioxidative, chelating, and DNA-protective effects of selected essential oil components (eugenol, carvacrol, thymol, borneol, eucalyptol) of plants and intact Rosmarinus officinalis oil. J Agric Food Chem 2014;62;6632-9. DOI: https://doi.org/10.1021/jf501006y
Halm MA. Essential oils for management of symptoms in critically ill patients. Ame J Crit Care 2008;17:160-3. DOI: https://doi.org/10.4037/ajcc2008.17.2.160
Chaiwong S, Puttarak P, Sretrirutchai S, Kaewsuwan S. In Vitro Anti-inflammatory and Antioxidative Activities of Isolated Interruptins from Cyclosorus terminans. Lat Ame J Pharma 2019;38:1677-82.
Kadhum AAH, Al-Amiery AA, Musa AY, Mohamad AB. The antioxidant activity of new coumarin derivatives. Int J Mol Sci 2011;12:5747-61. DOI: https://doi.org/10.3390/ijms12095747
Muntané J, De la Mata M. Nitric oxide and cancer. World J Hepatol 2010;2:337-44. DOI: https://doi.org/10.4254/wjh.v2.i9.337

How to Cite

Chaiwong, S., Akkarasiritharattana, K., Jarmkom, K., & Amorndoljai, P. (2023). Antioxidation and anti-inflammatory activities of blended essential oil. Healthcare in Low-Resource Settings, 11(1). https://doi.org/10.4081/hls.2023.11548
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