https://doi.org/10.4081/gc.2023.11066

Prolonged liver transplantation survival and aging successfully

Vol. 9 No. 1 (2023)
Submitted: 5 December 2022
Accepted: 3 March 2023
Published: 8 May 2023
aging, liver transplantation, chronic disease, multimorbidity, successful aging
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Authors

Francesco Pollicino
https://orcid.org/0009-0005-4549-0490
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Italy.
Ligia J. Dominguez
ligia.dominguez@unipa.it
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo; Faculty of Medicine and Surgery, Kore University, Enna, Italy.
Mario Barbagallo
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Italy.

The traditional definition of successful aging as the absence of disease, disability, and cognitive impairment is not always applicable to patients with long survival despite complex multimorbidity. This case report details the situation of an 87-year-old man, currently partially self-sufficient and partially autonomous, without cognitive impairment, who has been affected with recurrent right knee osteomyelitis since the age of 6. A diagnosis of hepatitis C virus (HCV)-related liver cirrhosis at 41 led to liver transplantation at 56. The immunosuppressive anti-rejection therapy caused a relapse of chronic osteomyelitis and HCV infection, a major cause of graft loss and shortened survival in HCV liver transplant recipients. Other pathologies were also diagnosed during his lifetime. This patient is an example of aging successfully despite complex multimorbidity and disproves the traditional concept of successful aging formerly described in the literature.

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How to Cite

Pollicino, F., Dominguez, L. J., & Barbagallo, M. (2023). Prolonged liver transplantation survival and aging successfully. Geriatric Care, 9(1). https://doi.org/10.4081/gc.2023.11066
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