https://doi.org/10.4081/gc.2022.11049
The role of comprehensive geriatric assessment in older patients affected by knee osteoarthritis: a systematic review
Submitted: 1 December 2022
Accepted: 23 December 2022
Published: 30 December 2022
Accepted: 23 December 2022
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Appendix: 26
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Osteoarthritis (OA) is one of the most common musculoskeletal diseases and highly prevalent in older people. Whilst the management of knee OA is usually multidisciplinary, the use of comprehensive geriatric assessment (CGA) for this condition is still limited. Given this background, with this systematic review, we summarized the current literature regarding the importance of CGA in people affected by knee OA. A systematic search across several databases was run until 10th April 2022 and updated on 21st November 2022 for any study investigating the use of CGA in patients with knee OA. The data were summarized descriptively. Among 295 articles initially included, three studies made in the context of the osteoarthritis initiative (OAI) were included. All the three studies used the OAI multidimensional prognostic index (MPI), a composite score derived from the CGA. Higher MPI values were associated with a higher risk of falls, cardiovascular conditions, and fractures across a follow-up period of 8 years and after adjusting for potential confounders. In conclusion, in this systematic review we summarized the current evidence of CGA in knee OA, finding that the MPI, a CGA derived tool, could be useful to early find people at higher risk of conditions that are associated with knee OA and therefore that can be the target of personalized interventions for preventing these conditions.
Murray CJ, Vos T, Lozano R, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2197-223.
DOI: https://doi.org/10.1016/S0140-6736(12)61689-4
Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ 2003;81:646-56.
Bijlsma JW, Berenbaum F, Lafeber FP. Osteoarthritis: an update with relevance for clinical practice. Lancet 2011;377:2115-26.
DOI: https://doi.org/10.1016/S0140-6736(11)60243-2
Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2163-96.
DOI: https://doi.org/10.1016/S0140-6736(12)61729-2
Nuesch E, Dieppe P, Reichenbach S, et al. All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study. BMJ 2011;342:d1165.
DOI: https://doi.org/10.1136/bmj.d1165
Bruyère O, Honvo G, Veronese N, et al. An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Semin Arthritis Rheum 2019 [Epub ahead of print].
DOI: https://doi.org/10.1016/j.semarthrit.2019.04.008
Nikolaus T, Specht-Leible N, Bach M, et al. A randomized trial of comprehensive geriatric assessment and home intervention in the care of hospitalized patients. Age Ageing 1999;28:543-50.
DOI: https://doi.org/10.1093/ageing/28.6.543
Pilotto A, Cella A, Pilotto A, et al. Three decades of comprehensive geriatric assessment: evidence coming from different healthcare settings and specific clinical conditions. J Am Med Dir Assoc 2017;18:192, e1-11.
DOI: https://doi.org/10.1016/j.jamda.2016.11.004
Pilotto A, Custodero C, Maggi S, et al. A multidimensional approach to frailty in older people. Ageing Res Rev 2020;60:1010-47.
DOI: https://doi.org/10.1016/j.arr.2020.101047
Weber A, Hung Mak S, Berenbaum F, et al. Association between osteoarthritis and increased risk of dementia: a systemic review and meta-analysis. Med 2019;98.
DOI: https://doi.org/10.1097/MD.0000000000014355
Veronese N, Stubbs B, Solmi M, et al. Osteoarthritis increases the risk of cardiovascular disease: data from the osteoarthritis initiative. J Nutr Health Aging 2018;22:371-6.
DOI: https://doi.org/10.1007/s12603-017-0941-0
Kim KW, Han JW, Cho HJ, et al. Association between comorbid depression and osteoarthritis symptom severity in patients with knee osteoarthritis. J Bone Joint Surg Am 2011;93:556-63.
DOI: https://doi.org/10.2106/JBJS.I.01344
Kool MB, Geenen R. Loneliness in patients with rheumatic diseases: the significance of invalidation and lack of social support. J Psychol 2012;146:229-41.
DOI: https://doi.org/10.1080/00223980.2011.606434
Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 2009;62:e1-34.
DOI: https://doi.org/10.1016/j.jclinepi.2009.06.006
Veronese N, Koyanagi A, Smith L, et al. Multidimensional frailty increases cardiovascular risk in older people: an 8-year longitudinal cohort study in the Osteoarthritis Initiative. Exp Gerontol 2021;147:1112-65.
DOI: https://doi.org/10.1016/j.exger.2021.111265
Veronese N, Siri G, Cella A, et al. The multidimensional prognostic index predicts falls in older people: an 8-year longitudinal cohort study of the osteoarthritis initiative. J Am Med Dir Assoc 2020;21:669-74.
DOI: https://doi.org/10.1016/j.jamda.2019.10.002
Veronese N, Smith L, Zigoura E, et al. Multidimensional prognostic index and the risk of fractures: an 8-year longitudinal cohort study in the Osteoarthritis Initiative. Arch Osteoporos 2022;17:1-8.
DOI: https://doi.org/10.1007/s11657-021-01015-3
McConnell S, Kolopack P, Davis AM. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC): a review of its utility and measurement properties. Arthrit Care Res 2001;45:453-61.
DOI: https://doi.org/10.1002/1529-0131(200110)45:5<453::AID-ART365>3.0.CO;2-W
Washburn RA, Smith KW, Jette AM, Janney CA. The physical activity scale for the elderly (PASE): development and evaluation. J Clin Epidemiol 1993;46:153-62.
DOI: https://doi.org/10.1016/0895-4356(93)90053-4
Sheehan TJ, Fifield J, Reisine S, Tennen H. The measurement structure of the Center for Epidemiologic Studies Depression scale. J Pers Assess 1995;64:507-21.
DOI: https://doi.org/10.1207/s15327752jpa6403_9
Roos EM, Lohmander LS. The knee injury and osteoarthritis outcome score (KOOS): from joint injury to osteoarthritis. Health Qual Life Outcomes 2003;1:1-8.
DOI: https://doi.org/10.1186/1477-7525-1-1
Polidori MC. Comprehensive geriatric assessment in patients with cognitive decline. Comprehen Geriatr Assess 2018;59-67.
Pilotto A, Polidori MC, Veronese N, et al. Association of antidementia drugs and mortality in community-dwelling frail older patients with dementia: the role of mortality risk assessment. J Am Med Dir Assoc 2018;19:162-8.
DOI: https://doi.org/10.1016/j.jamda.2017.08.017
Caillet P, Pamoukdjian F, Obraztsova A, Paillaud E. Comprehensive geriatric assessment in cancer patients. Comprehen Geriatr Assess 2018;111-21.
DOI: https://doi.org/10.1007/978-3-319-62503-4_10
Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 2007;25:1824-31.
DOI: https://doi.org/10.1200/JCO.2007.10.6559
Wieland D, Hirth V. Comprehensive geriatric assessment. Cancer Control 2003;10:454-62.
DOI: https://doi.org/10.1177/107327480301000603
Chaïbi P, Magné N, Breton S, et al. Influence of geriatric consultation with comprehensive geriatric assessment on final therapeutic decision in elderly cancer patients. Crit Rev Onco Hematol 2011;79:302-7.
DOI: https://doi.org/10.1016/j.critrevonc.2010.08.004
Brunello A, Fontana A, Zafferri V, et al. Development of an oncological-multidimensional prognostic index (Onco-MPI) for mortality prediction in older cancer patients. J Cancer Res Clin Oncol 2016;142:1069-77.
DOI: https://doi.org/10.1007/s00432-015-2088-x
Wongrakpanich S, Wongrakpanich A, Melhado K, Rangaswami J. A comprehensive review of non-steroidal anti-inflammatory drug use in the elderly. Aging Dis 2018;9:143.
DOI: https://doi.org/10.14336/AD.2017.0306
Primorac D, Molnar V, Matišić V, et al. Comprehensive review of knee osteoarthritis pharmacological treatment and the latest professional societies’ guidelines. Pharmaceuticals 2021;14:205.
DOI: https://doi.org/10.3390/ph14030205
Cruz-Jentoft AJ, Daragjati J, Fratiglioni L, et al. Using the multidimensional prognostic index (MPI) to improve cost-effectiveness of interventions in multimorbid frail older persons: results and final recommendations from the MPI_AGE European Project. Aging Clin Exp Res 2020;32:861-8.
DOI: https://doi.org/10.1007/s40520-020-01516-0
Thomas E, Dunn KM, Mallen C, Peat G. A prognostic approach to defining chronic pain: application to knee pain in older adults. Pain 2008;139:389-97.
DOI: https://doi.org/10.1016/j.pain.2008.05.010
How to Cite
Veronese, N., Fazzari, A., Caudal, M., Polidori, M. C., Topinkova, E., Mattace Raso, F., Barbagelata, M., Barbagallo, M., & Pilotto, A. (2022). The role of comprehensive geriatric assessment in older patients affected by knee osteoarthritis: a systematic review. Geriatric Care, 8(3). https://doi.org/10.4081/gc.2022.11049
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