https://doi.org/10.4081/gc.2022.10668

A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician

Vol. 8 No. 2 (2022)
Submitted: 12 June 2022
Accepted: 6 September 2022
Published: 22 September 2022
Elderly-onset Sjögren’s syndrome, sicca syndrome, diagnostic and classification criteria, seronegative subset of disease, labial salivary glands biopsy.
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Authors

Ciro Manzo
manzoreumatologo@libero.it
Internal and Geriatric Medicine Department, Rheumatologic Outpatient Clinic, Health District no. 59, Azienda Sanitaria Locale Napoli 3 Sud, Italy.
Alberto Castagna
https://orcid.org/0000-0001-9136-2055
Primary Care Department, Health District of Soverato, Azienda Sanitaria Provinciale Catanzaro, Italy.
Giovanni Ruotolo
Geriatric Medicine Department, Azienda Ospedaliera ‘Pugliese-Ciaccio’, Catanzaro, Italy.

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease where xerophthalmia, xerostomia and presence of anti-SSA and anti-SSB antibodies are typical features. Its prevalence is higher in over-65 aged population than in other age groups. In the elderly, pSS diagnosis comes up against a whole series of critical points that may favor its misdiagnosis. The aim of our article is to discuss the most relevant of them: the frequent occurrence of a seronegative subset, the presence of systemic features not related to sicca syndrome, the sicca syndrome as iatrogenic manifestation and the possibility of a biopsy false negative of labial salivary glands.

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How to Cite

Manzo, C., Castagna, A. ., & Ruotolo, G. . (2022). A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician. Geriatric Care, 8(2). https://doi.org/10.4081/gc.2022.10668

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