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A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation

Authors

Franco Lai
franco.lai@uslcentro.toscana.it
Emergency Department, Santo Stefano Hospital, Prato, Italy.
Lorenzo Pelagatti
Emergency Department, Santo Stefano Hospital, Prato, Italy.
Chiara Pagnini
School of Medicine, University of Florence, Florence, Italy.
Alessio Baldini
Emergency Department, Santo Stefano Hospital, Prato, Italy.
Daniele Versari
Emergency Department, Santo Stefano Hospital, Prato, Italy.
Simone Magazzini
Emergency Department, Santo Stefano Hospital, Prato, Italy.

A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case of a 19-year-old male of oriental-Asiatic origin admitted unconscious to ED with alcoholic fetor: on electrocardiogram a significant and widespread STsegment elevation was observed. A bedside echocardiography showed no abnormalities in segmental kinetics; therefore electrocardiogram- alterations could be related to a coronary spasm. The literature is poor about this effect induced by acute alcohol ingestion: the pathophysiological mechanism at the base of the abnormal muscle contractility, seems to be related to an impairment in cyclic guanosine monophosphate production, although a second and less probable hypothesis could be an altered intracellular concentration of calcium levels.

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How to Cite

Lai, F., Pelagatti, L., Pagnini, C., Baldini, A., Versari, D., & Magazzini, S. (2020). A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation. Emergency Care Journal, 16(1). https://doi.org/10.4081/ecj.2020.8596

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