Aortic dissection presenting with respiratory failure: case report and literature

Submitted: 10 May 2024
Accepted: 31 July 2024
Published: 2 September 2024
Abstract Views: 230
PDF: 98
Supplementary Materials: 29
VIDEO: 45
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Due to its nonspecific symptoms, in several cases, Acute Aortic Dissection (AAD) is a difficult-to-diagnose urgent condition. The torn intimal layer initiates a false lumen, which can potentially propagate and cause life-threatening ruptures or organ ischemia. Intramural hematoma can rarely develop inside the false lumen, resulting in compression of surrounding structures and worsening the patient’s prognosis. We report a case of AAD - Stanford Type A complicated by an intramural hematoma compressing the pulmonary artery, accompanied by a discussion of relevant literature. This patient presented to the emergency department with acute respiratory distress; clinical and initial diagnostic findings mimicked pulmonary embolism. However, a systematic differential evaluation supported by point-of-care ultrasound allowed a prompt diagnosis of AAD and avoided fixation errors.

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Isselbacher EM, Preventza O, Hamilton Black J, et al. 2022 ACC/AHA Guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Am Coll Cardio 2022;80:e223-393.
Mclatchie R, Reed MJ, Freeman N, et al. Diagnosis of Acute Aortic Syndrome in the Emergency Department ( DAShED ) study : an observational cohort study of people attending the emergency department with symptoms consistent with acute aortic syndrome. Emerg Med J. 2024;41:136-44. DOI: https://doi.org/10.1136/emermed-2023-213266
Baliyan V, Parakh A, Prabhakar AM, Hedgire S. Acute aortic syndromes and aortic emergencies. Cardiovasc Diagn Ther 2018;8:S82-96. DOI: https://doi.org/10.21037/cdt.2018.03.02
Bossone E, Labounty TM, Eagle KA. Acute aortic syndromes: diagnosis and management, an update. Eur Heart J 2018;39:739-49. DOI: https://doi.org/10.1093/eurheartj/ehx319
Evangelista A, Isselbacher EM, Bossone E, et al. Insights from the international registry of acute aortic dissection: a 20-year experience of collaborative clinical research. Circulation 2018;137:1846-60. DOI: https://doi.org/10.1161/CIRCULATIONAHA.117.031264
Hagan PG, Nienaber CA, Isselbacher EM, et al. The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA 2000;283:897-903. DOI: https://doi.org/10.1001/jama.283.7.897
Stepinska J, Lettino M, Ahrens I, et al. Diagnosis and risk stratification of chest pain patients in the emergency department: focus on acute coronary syndromes. A position paper of the Acute Cardiovascular Care Association. Eur Hear J Acute Cardiovasc Care 2020;9:76-89. DOI: https://doi.org/10.1177/2048872619885346
Vercelli A, Berardi E, Poggiali E. Comments on “Why do emergency department clinicians miss acute aortic syndrome? A case series and descriptive analysis”. Emerg Care J 2023;19:11433. DOI: https://doi.org/10.4081/ecj.2023.11433
Huang YC, Sung SF, Liu KT. Painless Acute Aortic Dissection may present as a stroke; risky markers that could be identified on hospital arrival. J Acute Med 2017;7:93.
Usui T, Suzuki K, Niinami H, Sakai S. Aortic dissection diagnosed on stroke computed tomography protocol: a case report. J Med Case Rep 2021;15:4-9. DOI: https://doi.org/10.1186/s13256-021-02850-1
Harris KM, Strauss CE, Eagle KA, et al. Correlates of delayed recognition and treatment of acute type a aortic dissection: the International Registry Of Acute Aortic Dissection (IRAD). Circulation 2011;124:1911-8. DOI: https://doi.org/10.1161/CIRCULATIONAHA.110.006320
McLatchie R, Wilson S, Reed MJ, et al. Why do emergency department clinicians miss acute aortic syndrome? A case series and descriptive analysis. Emerg Care J 2023;19:11153. DOI: https://doi.org/10.4081/ecj.2023.11153
Sasaki S, Watanabe H, Shibayama K, et al. Three-dimensional transesophageal echocardiographic evaluation of coronary involvement in patients with Acute Type A Aortic Dissection. J Am Soc Echocardiogr 2013;26:837-45. DOI: https://doi.org/10.1016/j.echo.2013.05.001
Kawahito K, Adachi H, Murata SI, et al. Coronary malperfusion due to Type A Aortic Dissection: mechanism and surgical management. Ann Thorac Surg 2003;76:1471-6. DOI: https://doi.org/10.1016/S0003-4975(03)00899-3
Suzuki T, Distante A, Zizza A, et al. Diagnosis of acute aortic dissection by D-dimer: the International Registry Of Acute Aortic Dissection substudy on Biomarkers (IRAD-bio) experience. Circulation 2009;119:2702-7. DOI: https://doi.org/10.1161/CIRCULATIONAHA.108.833004
Nazerian P, Mueller C, De Matos Soeiro A, et al. Diagnostic accuracy of the Aortic Dissection Detection risk score plus D-dimer for acute aortic syndromes the ADvISED prospective multicenter study. Circulation 2018;137:250-8. DOI: https://doi.org/10.1161/CIRCULATIONAHA.117.029457
Wang Y, Yu H, Cao Y, Wan Z. Early screening for aortic dissection with Point-of-Care Ultrasound by emergency physicians: a prospective pilot study. J Ultrasound Med 2020;39:1309-15. DOI: https://doi.org/10.1002/jum.15223
Fojtik JP, Costantino TG, Dean AJ. The diagnosis of aortic dissection by emergency medicine ultrasound. J Emerg Med 2007;32:191-6. DOI: https://doi.org/10.1016/j.jemermed.2006.07.020
Evangelista A, Maldonado G, Gruosso D, et al. The current role of echocardiography in acute aortic syndrome. Echo Res Pract 2019;6:R53-63. DOI: https://doi.org/10.1530/ERP-18-0058
Gibbons RC, Smith D, Feig R, et al. The Sonographic Protocol for the Emergent Evaluation of Aortic Dissections (SPEED protocol): a multicenter, prospective, observational study. Acad Emerg Med 2024;31:112-8. DOI: https://doi.org/10.1111/acem.14839
Ghane MR, Gharib MH, Ebrahimi A, et al. Accuracy of Rapid Ultrasound in Shock (RUSH) exam for diagnosis of shock in critically ill patients. Trauma Mon 2015;20:20095. DOI: https://doi.org/10.5812/traumamon.20095
Meredith EL, Masani ND. Echocardiography in the emergency assessment of acute aortic syndromes. Eur J Echocardiogr 2009;10:i31-9. DOI: https://doi.org/10.1093/ejechocard/jen251
Flachskampf FA, Wouters PF, Edvardsen T, et al. Recommendations for transoesophageal echocardiography: EACVI update 2014. Eur Heart J - Cardiovasc Imag 2014;15:353-65. DOI: https://doi.org/10.1093/ehjci/jeu015
Boileau C, Bossone E, Di Bartolomeo R, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases. Eur Heart J 2014;35:2873-926. DOI: https://doi.org/10.1093/eurheartj/ehu281
Masuo M, Takano H, Takamoto S, et al. Pulmonary artery obstruction caused by thoracic aortic dissection - a case with unique pathological findings. Circ J 2004;68:392-5. DOI: https://doi.org/10.1253/circj.68.392
Dong HK, Sang WR, Choi YS, Ahn BH. Aortic dissection presenting with secondary pulmonary hypertension caused by compression of the pulmonary artery by dissecting hematoma: a case report. Korean J Radiol 2004;5:139-42.
De Silva RJ, Hosseinpour R, Screaton N, et al. Right pulmonary artery occlusion by an acute dissecting aneurysm of the ascending aorta. J Cardiothorac Surg 2006;1:1-3. DOI: https://doi.org/10.1186/1749-8090-1-29
Munín M, Goerner MS, Lombardero M, et al. Thickening of the pulmonary artery wall in acute intramural hematoma of the ascending aorta. Cardiovasc Ultrasound 2007;5:1-3. DOI: https://doi.org/10.1186/1476-7120-5-1
Sueyoshi E, Sakamoto I, Uetani M, et al. CT findings of ruptured intramural hematoma of the aorta extending along the pulmonary artery. Cardiovasc Intervent Radiol 2007;30:321-3. DOI: https://doi.org/10.1007/s00270-005-0388-2
Sheu JJ, Fu M, Lee FY, et al. Ascending aortic dissecting aneurysm with isolated right pulmonary arterial medial intramural hematoma. Ann Thorac Surg 2008;85:2127-8. DOI: https://doi.org/10.1016/j.athoracsur.2007.12.054
Sueyoshi E, Matsuoka Y, Sakamoto I, Uetani M. CT and clinical features of hemorrhage extending along the pulmonary artery due to ruptured aortic dissection. Eur Radiol 2009;19:1166-74. DOI: https://doi.org/10.1007/s00330-008-1272-7
Inoue Y, Takahashi R, Kashima I, Tsutsumi K. Mediastinal hematoma: another lethal sign of aortic dissection. Interact Cardiovasc Thorac Surg 2009;8:275-6. DOI: https://doi.org/10.1510/icvts.2008.188979
Can M, Tanboga IH, Akgun T, et al. Type A intramural hematoma presenting with acute right heart failure caused by compression of the main pulmonary artery: a case report. Ann Vasc Surg 2009;23:535.e11-4. DOI: https://doi.org/10.1016/j.avsg.2008.08.024
Podbregar M, Gabrijelčî T. Acute right heart overload due to pulmonary artery obstruction caused by ruptured aortic dissection. Eur Heart J 2011;32:517. DOI: https://doi.org/10.1093/eurheartj/ehq366
Miele V, Merola MG, Roncacci A, Ianniello S. Pulmonary artery intramural hematoma associated with Stanford type B aortic dissection. J Cardiovasc Comput Tomogr 2015;9:466-8. DOI: https://doi.org/10.1016/j.jcct.2015.05.004
Okiwelu N, Finn C, Vanden Driesen R, et al. Ruptured penetrating ulcer of the ascending aorta with pulmonary artery compression. Asian Cardiovasc Thorac Ann 2016;24:266-8. DOI: https://doi.org/10.1177/0218492314557870
Wakakuri H, Hyodo H, Ohara T, Yasutake M. Perivascular hematoma along pulmonary artery complicating aortic dissection. J Nippon Med Sch 2016;83:182-3. DOI: https://doi.org/10.1272/jnms.83.182
Talla K, Dmytriw AA, Nguyen E. Acute Type A Aortic Dissection with mediastinal hematoma mimicking massive pulmonary embolus. Int J Cardiovasc Imaging 2017;33:259-60. DOI: https://doi.org/10.1007/s10554-016-0989-7
Yamazaki S, Funakoshi H. Pulmonary artery stenosis due to aortic dissection. Eur Hear J - Cardiovasc Imaging 2019;20:1019. DOI: https://doi.org/10.1093/ehjci/jez053
Chong WH, Saha BK, Wang C, Beegle S. Type A aortic dissection mimicking saddle pulmonary embolism on CT imaging. J Am Coll Emerg Physicians Open 2020;1:132. DOI: https://doi.org/10.1002/emp2.12026
Bradette S, Béland M, Lalonde C. Pulmonary artery compression by hematoma, a rare but life-threatening complication of Stanford type A aortic dissection. J Card Surg 2020;35:2808-10. DOI: https://doi.org/10.1111/jocs.14900
Warisawa T, Kotoku A, Miyauchi R, et al. Pulmonary artery occlusion due to abrupt pinhole rupture of aortic arch aneurysm. JACC Cardiovasc Interv 2021;14:e15-6. DOI: https://doi.org/10.1016/j.jcin.2020.11.028
Hirata K, Ishimine T, Nakayama I, et al. Unilateral left pulmonary edema caused by contained rupture of the ascending aortic dissection. Intern Med 2021;60:751-3. DOI: https://doi.org/10.2169/internalmedicine.5750-20
Gros-Gean J, Lebecque O, Nchimi A, Vlad MM. Case series: pulmonary artery intramural hematoma in Stanford Type A Acute Aortic Dissection. J Belgian Soc Radiol 2021;105:34. DOI: https://doi.org/10.5334/jbsr.2446
Dong HK, Sang WR, Choi YS, Ahn BH. Aortic dissection presenting with secondary pulmonary hypertension caused by compression of the pulmonary artery by dissecting hematoma: a case report. Korean J Radiol 2004;5:139-42. DOI: https://doi.org/10.3348/kjr.2004.5.2.139
Bedolla J, Pines JM. Cognitive biases and mitigation strategies in emergency diagnosis. In Evidence‐Based Emergency Care: Diagnostic Testing and Clinical Decision Rules, Third Edition, Pines JM, Belollio F, Carpenter CR, Raja AS (eds.), John Wiley & Sons Ltd, 2023. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119616870.ch60 DOI: https://doi.org/10.1002/9781119616870.ch60
Patel PA, Bavaria JE, Ghadimi K, et al. Aortic regurgitation in Acute Type-A Aortic Dissection: a clinical classification for the perioperative echocardiographer in the era of the functional aortic annulus. J Cardiothorac Vasc Anesth 2018;32:586-97. DOI: https://doi.org/10.1053/j.jvca.2017.06.014
Kagiyama N, Otsuki Y, Tsunoda M, Yoshitaka H. Multimodality imaging in aortic arch aneurysm ruptured into the pulmonary artery. Ann Thorac Surg 2019;107:e217. DOI: https://doi.org/10.1016/j.athoracsur.2018.08.088
Kanaan T, Abdelrahman AS, Jaber J, et al. Type A aortic dissection with intramural hematoma: a challenging diagnosis. Cureus 2023;15:e33300. DOI: https://doi.org/10.7759/cureus.33300
Plack D, Rehfeldt K, Nelson J, Kauss M. Pulmonary artery sheath hematoma. Ann Card Anaesth 2021;24:232. DOI: https://doi.org/10.4103/aca.ACA_135_20
Konstantinides SV, Humbert M, Sian C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 2020;41:543-603. DOI: https://doi.org/10.1093/eurheartj/ehz405
Humbert M, Hoeper MM, Berger RMF, et al. 2022 ESC / ERS Guidelines for the diagnosis and treatment of pulmonary hypertension developed by the task force for the diagnosis and treatment of (ESC) and the European Respiratory Society (ERS). Eur Heart J 2022;43:3618-731. DOI: https://doi.org/10.1093/eurheartj/ehac237
Morello F, Bima P, Castelli M, et al. Diagnosis of acute aortic syndromes with ultrasound and d-dimer: the PROFUNDUS study. Eur J Intern Med 2024:S0953-6205(24)00234-6.

How to Cite

Gherardi, S., Ippolito, R., Pasqualin, S., Cianci, V., & Paganini, M. (2024). Aortic dissection presenting with respiratory failure: case report and literature. Emergency Care Journal, 20(3). https://doi.org/10.4081/ecj.2024.12633