https://doi.org/10.4081/ecj.2024.12268
Prognostic value of lung ultrasound score performed in the Emergency Department in COVID-19 patients: a prospective multicenter study in central Italy
Submitted: 9 January 2024
Accepted: 13 February 2024
Published: 4 March 2024
Accepted: 13 February 2024
Abstract Views: 1496
PDF: 402
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Lung ultrasound (LUS) is an essential tool for respiratory disease differential diagnosis at Emergency Department (ED), due to easy applicability and safety. During Sars-Cov 2 pandemic, LUS was widely used in every setting. This study aims to demonstrate the prognostic role of LUS independently of other factors and the identification of an LUS score cut-off to be applied in the ED. A multi-center prospective study was conducted on 285 patients, 123 from Pisa University Hospital, 162 from S. Maria Misericordia Hospital of Perugia. All patients received LUS examination by expert sonographers within 48 hours of admission with the same methodology. Univariate logistic analysis demonstrated that LUS is a mortality predictor, OR 2.8 (CL1.5-5.1). Using LUS score cut-off 1.3, the OR was 6.7 (CL2.7-1.6). In multivariate logistic analysis, LUS score significantly predicted death, independently of other factors. ROC curves comparison demonstrated that the introduction of LUS score <1.3 to a multifactorial model improved the association with mortality (AUC 0.76vs0.84, p=0.04). LUS combined with clinical, anamnestic, laboratory, and blood gas parameters, would allow an effective prognostic stratification in Sars-Cov2 patients at ED.
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How to Cite
Barbieri, G., De Vuono, S., Gargani, L., Berisha, S., Spinelli, S., Del Carlo, C., Deri, C., D’Angelo, G., Groff, P., & Ghiadoni, L. (2024). Prognostic value of lung ultrasound score performed in the Emergency Department in COVID-19 patients: a prospective multicenter study in central Italy. Emergency Care Journal, 20(1). https://doi.org/10.4081/ecj.2024.12268
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