https://doi.org/10.4081/ecj.2023.11655
Estimated plasma volume status can help identify patients with sepsis at risk of death within 30 days in the emergency department
Submitted: 11 August 2023
Accepted: 13 October 2023
Published: 20 October 2023
Accepted: 13 October 2023
Abstract Views: 682
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
For patients with sepsis in the Emergency Department (ED), early risk stratification is important to improve prognosis. The study aimed to evaluate the predictive role of estimated plasma volume (ePVS) on admission to the ED. All sepsis patients who were admitted to our ED in 2021, were included in this prospective study. Multivariate models adjusted for patients' clinical characteristics were used to assess the contribution of ePVS to the independent prediction of death at 30 days. A total of 455 septic patients were enrolled and 16.9% of patients died. Patients who survived to 30 days had a mean ePVS of 5.19, while those who died at 30 days had a value of 5.74 (p=0.004). ePVS was an independent risk factor for 30-day mortality with an adjusted OR of 1.211 (95% CI 1.004–1.460, p=0.045). The AUROC of ePVS was 0.619 (95% CI 0.545–0.689). Decision tree analysis showed a predictive role for ePVS in less severe patients. In septic patients, ePVS is an independent predictor of 30-day mortality and may improve risk prediction in less severe patients.
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How to Cite
Turcato, G., Zaboli, A., Sibilio, S., Mian, M., & Brigo, F. (2023). Estimated plasma volume status can help identify patients with sepsis at risk of death within 30 days in the emergency department. Emergency Care Journal, 19(4). https://doi.org/10.4081/ecj.2023.11655
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