0
0
0
0
Smart Citations
0
0
0
0
Citing PublicationsSupportingMentioningContrasting
View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Emerging immunological challenges in post-COVID individuals: insights from a case series and review

Authors

The Coronavirus Disease 2019 (COVID-19) pandemic has unveiled diverse immunological complications extending beyond the acute phase of infection. We present a case series of four patients who developed autoimmune vasculitis and sarcoidosis post-recovery from COVID-19. Case presentations include recurrent fever and respiratory symptoms in a 36-year-old female, granulomatous liver lesions in a 63-year-old male, progressive dyspnea in a 44-year-old female, and diffuse alveolar hemorrhage in a 74-year-old female following severe pneumonia. These cases underscore the importance of vigilance for immunological sequelae in post-COVID-19 patients, particularly those with predisposing comorbidities. We tried to elucidate pathophysiological mechanisms and optimize management strategies for these rare but clinically significant manifestations.

Al-Ani F, Chehade S, Lazo-Langner A. Thrombosis risk associated with COVID-19 infection. A scoping review. Thromb Res. 2020;192:152-60. DOI: https://doi.org/10.1016/j.thromres.2020.05.039
Fox SE, Akmatbekov A, Harbert JL, et al. Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans. Lancet Respir Med. 2020;8:681-6. DOI: https://doi.org/10.1016/S2213-2600(20)30243-5
British Society for Immunology. Long-term Immunological health consequences of COVID-19. 2020. Available from: https://www.immunology.org/sites/default/files/2022-09/BSI_Long_Term_Immunology_Health_Consequences_Covid-19.pdf
Lin Y, Askonas B. Biological properties of an influenza A virus‐specific killer T cell clone. Inhibition of virus replication in vivo and induction of delayed‐type hypersensitivity reactions. J Exp Med. 1981;154:225‐34. DOI: https://doi.org/10.1084/jem.154.2.225
Zhao H, Shen D, Zhou H, et al. Guillain‐Barre syndrome associated with SARS‐CoV‐2 infection: causality or coincidence? The Lancet Neurology. 2020;19:383‐4. DOI: https://doi.org/10.1016/S1474-4422(20)30109-5
Ray A. Miller Fisher syndrome and COVID‐19: is there a link? BMJ Case Rep. 2020;13:e236419. DOI: https://doi.org/10.1136/bcr-2020-236419
Guan W‐J, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708‐20. DOI: https://doi.org/10.1056/NEJMoa2002032
Hindilerden F, Yonal‐Hindilerden I, Akar E, et al. Severe autoimmune hemolytic anemia in COVID‐19 infection, safely treated with steroids. Mediterr J Hematol Infect Dis. 2020;12:2020053 DOI: https://doi.org/10.4084/mjhid.2020.053
Watts RA, Lane SE, Bentham G, Scott DG. Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. Arthritis Rheum. 2000;43:414-9. DOI: https://doi.org/10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0
Gonzalez-Gay MA, Garcia-Porrua C, Guerrero J, et al. The epidemiology of the primary systemic vasculitides in northwest Spain: implications of the Chapel Hill Consensus Conference definitions. Arthritis Rheum. 2003;49:388-93. DOI: https://doi.org/10.1002/art.11115
Mohammad AJ, Jacobsson LT, Westman KW, et al. Incidence and survival rates in Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa. Rheumatology (Oxford). 2009;48:1560-5. DOI: https://doi.org/10.1093/rheumatology/kep304
Caso F, Costa L, Ruscitti P. Could Sars-Coronavirus-2 trigger autoimmune and / or autoinflammatory mechanisms in genetically predisposed subjects? Autoimmune Rev. 2020;19:102524. DOI: https://doi.org/10.1016/j.autrev.2020.102524
Li G., Chen X., Xu A. Profile of specific antibodies to the SARS-associated coronavirus. N. Engl. J. Med. 2003;349:508-9. DOI: https://doi.org/10.1056/NEJM200307313490520
Mubarak A, Alturaiki W, Hemida MG. Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine Development. Journal of Immunology Research. 2019;2019:6491738 DOI: https://doi.org/10.1155/2019/6491738
Xu X-W, Wu X-X, Jiang X-G, et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series. BMJ 2020;368:m606. DOI: https://doi.org/10.1136/bmj.m606
García LF. Immune response, inflammation, and the clinical spectrum of COVID-19. Front. Immunol. 2020;11:1441. DOI: https://doi.org/10.3389/fimmu.2020.01441
Gazzaruso C, Stella NC, Mariani G, et al. High prevalence of antinuclear antibodies and lupus anticoagulant in patients hospitalized for SARS-CoV2 pneumonia. Clin. Rheumatol. 2020;39:2095-7. DOI: https://doi.org/10.1007/s10067-020-05180-7

How to Cite

Karmakar, S., & Sharma, P. (2024). Emerging immunological challenges in post-COVID individuals: insights from a case series and review. Chest Disease Reports, 12(1). https://doi.org/10.4081/cdr.12.12659