Association of Obstructive Sleep Apnea with co-morbidities in smokers versus non-smokers - an observational study

Submitted: 12 March 2024
Accepted: 22 May 2024
Published: 17 July 2024
Abstract Views: 72
PDF: 32
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Obstructive Sleep Apnea (OSA) and smoking are important global health issues that are widely prevalent. Both are independently associated with cardiovascular, respiratory, metabolic, neurological, psychiatric, and endocrinological abnormalities and cancer, leading to premature death. Whether coexistent OSA and smoking worsen multisystem abnormalities is inconclusive. Therefore, this study was done to find the association between OSA and other morbidities among smokers and non-smokers. The objectives of this study were i) to evaluate the association of OSA with co-morbidities in smokers and non-smokers and ii) to compare the severity of OSA in smokers and non-smokers.

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Citations

American Academy of Sleep Medicine (AASM). AASM manual for the scoring of sleep and associated events: rules, terminology, and technical specifications. 2007. Available from: https://aasm.org/clinical-resources/scoring-manual/
Singh SK, Tentu AK, Singh S, et al. Association of metabolic syndrome in obstructive sleep apnoea patients: an experience from zonal care tertiary hospital in Eastern India. Indian J Respir Care. 2020:9:71-6. DOI: https://doi.org/10.4103/ijrc.ijrc_36_19
Udwadia ZF, Doshi AV, Lonkar SG, Singh CI. Prevalence of sleep-disordered breathing and sleep apnea in middle-aged urban Indian men. Am J Respir Crit Care Med. 2004;169:168-73. DOI: https://doi.org/10.1164/rccm.200302-265OC
Sharma SK, Kumpawat S, Banga A, Goel A. Prevalence and risk factors of obstructive sleep apnea syndrome in a population of Delhi, India. Chest. 2006;130:149-56. DOI: https://doi.org/10.1378/chest.130.1.149
Lui MMS, Mak JC, Lai AY, et al. The impact of obstructive sleep apnoea and tobacco smoking on endothelial function. Respiration. 2016;91:124-31. DOI: https://doi.org/10.1159/000443527
Gray EL, McKenzie DK, Eckert DJ. Obstructive sleep apnoea without obesity is common and difficult to treat: Evidence for a distinct pathophysiological phenotype. J Clin Sleep Med. 2017;13:81-8. DOI: https://doi.org/10.5664/jcsm.6394
Krishnan V, Dixon Williams S, Thornton JD. Where there is smoke there is sleep apnoea: exploring the relationship between smoking and sleep apnoea. Chest. 2014:146:1673-80. DOI: https://doi.org/10.1378/chest.14-0772
Jha P, Ranmasundarahettige C, Landsman V. 21st century-hazards of smoking and benefits of cessation in the United States. N Engl J Med. 2013:368:341-50. DOI: https://doi.org/10.1056/NEJMsa1211128
Jha P. Avoidable global cancer deaths and total deaths from smoking. Nat Rev Cancer. 2009;9:655-64. DOI: https://doi.org/10.1038/nrc2703
Zhu H, Xu H, Chen R, et al. Smoking, obstructive sleep apnoea syndrome and their combined effects on metabolic parameters: evidence from a large cross-sectional study. Sci Rep. 2017;7:8851. DOI: https://doi.org/10.1038/s41598-017-08930-x
Kashyap R, Hock LM, Bowman TJ. Higher prevalence of smoking in patients diagnosed as having obstructive sleep apnoea. Sleep Breath. 2001;5:167-72. DOI: https://doi.org/10.1007/s11325-001-0167-5
Trenchea M, Dantes E, Velescu L, et al. The influence of smoking on snoring, obstructive sleep apnoea, and related co-morbidities. Chest. 2015;148:2280956. DOI: https://doi.org/10.1378/chest.2280956
Duran J, Esnoala S, Ramon R, Iztueta A. obstructive sleep apnoea-hypopnea and related clinical features in a population-based subjects aged 30-70 years. Am J Respir Crit Cre Med. 2001;163:685-9. DOI: https://doi.org/10.1164/ajrccm.163.3.2005065
Dacal Quintas R, Tumbeiro Novoa M, Alves Pérez MT, et al. Obstructive sleep apnea in normal weight patients: characteristics and comparison with overweight and obese patients. Arch Bronconeumol. 2013;49:513-7. DOI: https://doi.org/10.1016/j.arbr.2013.09.012
Owens Rl, Macrea MM, Teodorescu M. The overlaps of asthma and COPD: a focussed review. Respirology. 2017;22:1073-83. DOI: https://doi.org/10.1111/resp.13107
Martinez-Rivera C, Abad J, Fiz JA, et al. Usefulness of truncal obesity indices as predictive factors for obstructive sleep apnoea syndrome. Obesity. 2008:16:113-8. DOI: https://doi.org/10.1038/oby.2007.20
Hsu W-Y, Chiu N-Y, Chang C-C, et al. The association between cigarette smoking and obstructive sleep apnoea. Tob. Induc. Dis. 2019:17:27. DOI: https://doi.org/10.18332/tid/105893
Conway SG, Roizenblatt SS, Palombini L. Effect of smoking habits on sleep. Braz J Med Biol Res. 2008:41:722-7. DOI: https://doi.org/10.1590/S0100-879X2008000800014
Bielicki P, Byśkiniewicz K, Kumor M, et al. Obstructive sleep apnoea syndrome in younger and older age groups--differences and similarities. Pneumonol Alergol Pol. 2006;74:56-8. DOI: https://doi.org/10.5603/ARM.28070
Wetter DW, Young TB, Bidwell TR, et al. Smoking as a risk factor for sleep-disordered breathing. Arch Intern Med. 1994;154:2219-24. DOI: https://doi.org/10.1001/archinte.154.19.2219
Hoflstein V. Relationship between smoking and sleep apnoea in clinic population. Sleep. 2002;25:519-24. DOI: https://doi.org/10.1093/sleep/25.5.517
Audrain-Mc Govern J, Benowitz NL. Cigarette smoking, nicotine and body weight. Clin Pharmacol Ther. 2011;90:164-8. DOI: https://doi.org/10.1038/clpt.2011.105
Lavie L, Lavie P. Smoking interacts with sleep apnoea to increase cardiovascular risk. Sleep Med. 2008;9:247-53. DOI: https://doi.org/10.1016/j.sleep.2007.03.018
Steveling AH, Clarenbach CF, Miedlinger D, et al. Predictors of the overlap syndrome and its association with co-morbidities in patients with chronic obstructive pulmonary disease. Respiration. 2014;88:451-7. DOI: https://doi.org/10.1159/000368615
Sajkov D, Wang T, Saunders NA, et al. Continuous positive airway pressure treatment improves pulmonary hemodynamics in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2002;165:152-8. DOI: https://doi.org/10.1164/ajrccm.165.2.2010092
Sevilla-Montero J, Labrousse-Arias D, Fernández-Pérez C, et al. Cigarette smoke directly promotes pulmonary arterial remodeling and Kv7.4 channel dysfunction. Am J Respir Crit Care Med. 2021;203:1290-305. DOI: https://doi.org/10.1164/rccm.201911-2238OC
Pinto JA, Ribeiro DK, Cavallin AF, et al. Comorbidities associated with obstructive sleep apnoea: a retrospective study. Int Arch Otorhinolaryngol. 2016;20:145-50. DOI: https://doi.org/10.1055/s-0036-1579546
Shi Y, Cao Z, Xie Y, et al. Association between obstructive sleep apnea and thyroid function: a 10-year retrospective study. Sleep Medicine. 2023;103:106-15. DOI: https://doi.org/10.1016/j.sleep.2023.01.027
Soldin OP, Goughenour BE, Gilbert SZ, et al. Thyroid hormone levels associated with active and passive cigarette smoking. Thyroid. 2009:19:817-23. DOI: https://doi.org/10.1089/thy.2009.0023

How to Cite

Haran, A., Mamatha, S., & Ashwini, S. (2024). Association of Obstructive Sleep Apnea with co-morbidities in smokers versus non-smokers - an observational study. Chest Disease Reports, 12(1). https://doi.org/10.4081/cdr.12.12472