https://doi.org/10.4081/cdr.12.12297

Synchronous multiple neuroendocrine primary lung cancer with endobronchial extension in a never smoker - An unusual manifestation

Vol. 12 (2024): Early Access
Submitted: 18 January 2024
Accepted: 24 January 2024
Published: 26 January 2024
Multiple Primary Lung Cancer, Synchronous Lung Cancer primaries, neuroendocrine tumor, diagnostic challenge
Abstract Views: 637
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Authors

Vinay V
docvinayv@gmail.com
https://orcid.org/0000-0003-1691-2111
Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences (AIIMS), Patna, India.
Sushil Kumar Munjal
Chest Physician (SAG), India.
Jitendra Kumar Saini
Chest Specialist (Grade-SAG) and Head of Thoracic Oncology Clinic, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Gaurav Kumar Singh
Senior Resident, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Shibani Modi
Post Graduate Trainee, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Alpana Srivastava
Senior Pathologist, Department of Pathology, CORE Diagnostics, Delhi, India.

Synchronous Lung Cancer primaries (SLC) are uncommon, with diverse underlying histology, constituting only a small proportion. The scarcity also poses a challenge in formulating a standardized diagnostic approach. Consequently, the diagnostic and staging challenges for SLC are heightened, particularly when the tumors are located on opposite sides of the chest. We report an exceptionally rare phenomenon in synchronous multiple primary lung cancers with simultaneous occurrence of two neuroendocrine tumors with endobronchial extension, small cell carcinoma and typical carcinoid tumor. Immunohistochemistry proved valuable in confirming the diagnosis. Given the poor prognosis associated with such cases, an accurate diagnosis is crucial for determining appropriate treatment options.

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How to Cite

V, V., Munjal, S. K., Saini, J. K., Singh, G. K., Modi, S., & Srivastava, A. (2024). Synchronous multiple neuroendocrine primary lung cancer with endobronchial extension in a never smoker - An unusual manifestation. Chest Disease Reports, 12(1). https://doi.org/10.4081/cdr.12.12297
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