https://doi.org/10.4081/cdr.10.10651

Diagnostic dilemma of Wegener’s granulomatosis and its effective management: A rare case report and update

Vol. 10 (2022)
Submitted: 1 June 2022
Accepted: 27 June 2022
Published: 15 July 2022
Wegener's granulomatosis, granulomatosis with polyangiitis, diffuse alveolar haemorrhage, cANCA, diagnostic dilemma, rituximab
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Authors

Mahavir Modi
mmodirhc@gmail.com
Department of Pulmonary Medicine, Ruby Hall Clinic, Pune, Maharashtra, India.
Kaumudi Devi
Department of Pulmonary Medicine, Ruby Hall Clinic, Pune, Maharashtra, India.

Granulomatosis with Polyangiitis (GPA) is an uncommon condition belongs to the group of ANCA-associated necrotizing vasculitides. It is characterized by necrotizing granulomatosis of upper and lower respiratory system with coexisting glomerulonephritis. Its signs and symptoms are largely varied due to a wide spectrum of involvement sites. In the present case report, we describe a case of 26-year-old female presented to our centre with history of bilateral ear discharge, earache, and dry cough with a deviated mouth angle to left. Diagnostic work up was done and patient was treated with pulse methylprednisolone, plasmapheresis, and rituximab. Timely diagnosis and prompt initiation of the treatment has prevented the GPA progression and helped the patient to improve quickly. Currently, the patient is doing well and is in remission.

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How to Cite

Modi, M., & Devi, K. . (2022). Diagnostic dilemma of Wegener’s granulomatosis and its effective management: A rare case report and update. Chest Disease Reports, 10(1). https://doi.org/10.4081/cdr.10.10651
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