https://doi.org/10.4081/ejtm.2019.8899
Neurohypophyseal hormones and skeletal muscle: a tale of two faces
Submitted: 12 February 2020
Accepted: 18 February 2020
Published: 1 April 2020
Accepted: 18 February 2020
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The neurohypophyseal hormones vasopressin and oxytocin were invested, in recent years, with novel functions upon striated muscle, regulating its differentiation, trophism, and homeostasis. Recent studies highlight that these hormones not only target skeletal muscle but represent novel myokines. We discuss the possibility of exploiting the muscle hypertrophying activity of oxytocin to revert muscle atrophy, including cancer cachexia muscle wasting. Furthermore, the role of oxytocin in cardiac homeostasis and the possible role of cardiac atrophy as a concause of death in cachectic patients is discussed.
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Supporting Agencies
Sapienza UniversityHow to Cite
Benoni, A., Renzini, A., Cavioli, G., & Adamo, S. (2020). Neurohypophyseal hormones and skeletal muscle: a tale of two faces. European Journal of Translational Myology, 30(1), 53–57. https://doi.org/10.4081/ejtm.2019.8899
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