https://doi.org/10.4081/ejtm.2024.13432

Mobility Medicine: A call to unify hyper-fragmented specialties by abstracts sent to 2025Pdm3, and typescripts to Ejtm3, and Diagnostics

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Published: 12 December 2024
Padua Days on Muscle and Mobility Medicine, 2025Pdm3, European Journal of Translational Myology, Ejtm3, PAGEpress, Italy
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Authors

Ugo Carraro
ugo.carraro@unipd.it
https://orcid.org/0000-0002-0924-4998
CIR-Myo Translational Myology Lab, Dept. Biomedical Sciences, Via Ugo Bassi 58/B, I-35131 Padova, Italy, Italy.
Marie Sophie Alberty
International FES Centre®, Swiss Paraplegic Centre Nottwil, Switzerland.
Stephen Anton
Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, USA; Department of Clinical and Health Psychology, University of Florida, Gainesville, United States.
Elena Barbieri
Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino (PU), Italy.
Ines Bersch
International FES Centre®, Swiss Paraplegic Centre Nottwil, Switzerland.
Bert Blaauw
Department of Biomedical Sciences, University of Padova, Italy; Interdepartmental Research Centre of Myology, University of Padova, Italy.
Gerardo Bosco
Department of Biomedical Sciences, University of Padova, Italy; Interdepartmental Research Centre of Myology, University of Padova, Italy; Department of Biomedical Sciences: Environmental Physiology and Medicine Lab, University of Padova, Italy.
Riccardo Forni
Institute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik, Iceland.
Massimo Ganassi
Randall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.
Paolo Gargiulo
Institute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik, Iceland; Landspitali, University Hospital of Iceland, Reykjavik, Iceland.
Paulo Gentil
College of Physical Education and Dance, Federal University of Goias, Brazil.
Ashraf S. Gorgey
Spinal Cord Injury and Disorders Center, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, USA; School of Medicine, Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, Virginia, United States.
Christiaan Leeuwenburgh
Department of Physiology and Aging, College of Medicine, University of Florida, FL, United Arab Emirates.
Maria Chiara Maccarone
Department of Neuroscience, Rehabilitation Unit, University of Padova, Italy.
Alessandro Martini
Padova University Research Center "International Auditory Processing Project in Venice (I-APPROVE)", Department of Neurosciences, University of Padua, Italy.
Stefano Masiero
Department of Neuroscience, Rehabilitation Unit, University of Padova, Italy.
Winfried Mayr
Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.
Giuseppe Messina
Department of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Rome, Italy; PLab Research Institute, Palermo, Italy.
Aldo Morra
Synlab Euganea Medica, Padua, Italy; Synlab IRCCS SDN S.p.A., Neaple, Italy.
Marco Narici
Department of Biomedical Sciences, University of Padova, Italy; Interdepartmental Research Centre of Myology, University of Padova, Italy.
Kay Ohlendieck
Department of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland.
Philippe Perrin
Development, Adaptation and Handicap, Faculty of Medicine, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Amber Pond
Anatomy Department, Southern Illinois University School of Medicine, Carbondale, IL, United States.
Marco Quadrelli
Synlab Euganea Medica, Padua, Italy.
Riccardo Rosati
Department of Biomedical Surgical and Dental Sciences, University of Milan, Italy.
Piero Sestili
Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino (PU) , Italy.
Piera Smeriglio
Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, Italy.
H. Lee Sweeney
Myology Institute, University of Florida, Gainesville, Florida, United States.
Daniela Tavian
Laboratory of Cellular Biochemistry and Molecular Biology, CRIBENS, Università Cattolica del Sacro Cuore, Milan, Italy.
Gerd Fabian Volk
ENT-Department, Facial-Nerve-Center and Center of Rare Diseases, Jena University Hospital, Jena, Germany.

Mega scientific conferences increasingly suffer from the need for short and poster presentations without discussion. An alternative is to organize workshops in hotels large enough to accommodate all participants. This significantly increases the opportunities for constructive discussion during breakfasts, lunches, dinners and long evenings that can bring together experts of scientific and clinical sub-specialties and young fellows. Time for groups' discussions and new collaborations are increased so as the job opportunities for the young researchers. The Padova Muscle Days have offered in the previous thirty-five years these opportunities, which have matured into innovative and multidisciplinary results to the point that it came naturally to underline it with a neologism now included in the title of the 2025 event: “Mobility Medicine”, a discipline not yet officially recognised, that makes explicit the call for rejoining knowledges dispersed in sub-specialisations. The included program of the Padua Days on Muscle and Mobility Medicine 2025 (2025Pdm3) will be hosted at the Hotel Petrarca in Euganean Thermae (Padua, Italy) from 25 to 29 March 2025. It further testifies by listing unique Sessions that it is possible to organize valid countermeasures to the inevitable tendencies towards hyperspecialization that the explosive increase in scientific progress brings with it. Furthermore, the European Journal of Translational Myology and Mobility Medicine (Ejtm3) will accept typescripts on results presented at the 2025Pdm3, together with the Special Section: New Trends in Musculoskeletal Imaging of the MDPI (Basel) Journal Diagnostics, because diagnosis is essential to prevent, manage and follow-up not only neuro-metabolic-muscular disorders, but the unavoidable physiologicical decay of performances in early and late aging. Hoping many others share our dreams, we look forward to meeting you at 2025Pdm3 conference.

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Ravara B, Giuriati W, Maccarone MC, Kern H, Masiero S, Carraro U. Optimized progression of Full-Body In-Bed Gym workout: an educational case report. Eur J Transl Myol. 2023 Jun 23;33(2):11525. doi: 10.4081/ejtm.2023.11525. PMID: 37358234; PMCID: PMC10388607.
Zampieri S, Bersch I, Smeriglio P, Barbieri E, Boncompagni S, Maccarone MC, Carraro U. Program with last minute abstracts of the Padua Days on Muscle and Mobility Medicine, 27 February - 2 March, 2024 (2024Pdm3). Eur J Transl Myol. 2024 Feb 2. doi: 10.4081/ejtm.2024.12346. Epub ahead of print. PMID: 38305708.
Zampieri S, Narici MV, Gargiulo P, Carraro U. Abstracts of the 2023 Padua Days of Muscle and Mobility Medicine (2023Pdm3) to be held March 29 - April 1 at the Galileian Academy of Padua and at the Petrarca Hotel, Thermae of Euganean Hills, Padua, Italy. Eur J Transl Myol. 2023 Feb 10;33(1):11247. doi: 10.4081/ejtm.2023.11247. Epub ahead of print. PMID: 36786151; PMCID: PMC10141763.
Sweeney HL, Masiero S, Carraro U. The 2022 On-site Padua Days on Muscle and Mobility Medicine hosts the University of Florida Institute of Myology and the Wellstone Center, March 30 - April 3, 2022 at the University of Padua and Thermae of Euganean Hills, Padua, Italy: The collection of abstracts. Eur J Transl Myol. 2022 Mar 10;32(1):10440. doi: 10.4081/ejtm.2022.10440. PMID: 35272451; PMCID: PMC8992680.
Carraro U, Yablonka-Reuveni Z. Translational research on Myology and Mobility Medicine: 2021 semi-virtual PDM3 from Thermae of Euganean Hills, May 26 - 29, 2021. Eur J Transl Myol. 2021 Mar 18;31(1):9743. doi: 10.4081/ejtm.2021.9743. PMID: 33733717; PMCID: PMC8056169.
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Carraro U. Collection of the Abstracts of the 2019Sp PMD: Translational Myology and Mobility Medicine. Eur J Transl Myol. 2019 Mar 11;29(1):8155. doi: 10.4081/ejtm.2019.8155. PMID: 31019666; PMCID: PMC6460219.
Carraro U. Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial - Chapter I - Foreword. Eur J Transl Myol. 2018 Feb 20;28(1):7363. doi: 10.4081/ejtm.2018.7363. PMID: 29686822; PMCID: PMC5895991.
Carraro U. 2017Spring PaduaMuscleDays, roots and byproducts. Eur J Transl Myol. 2017 Jun 27;27(2):6810. doi: 10.4081/ejtm.2017.6810. PMID: 28713538; PMCID: PMC5505085.
Ugo Carraro, CIR-Myo Translational Myology Lab, Dept. Biomedical Sciences, Via Ugo Bassi 58/B, I-35131 Padova, Italy

CURRICULUM VITAE: Prof. UGO CARRARO

ORCID iD: https://orcid.org/0000-0002-0924-4998

Prof. Ugo Carraro, M.D.,

Senior Scholar of the University of Padova, Italy

Department of Biomedical Sciences, University of Padova, Italy

phone: +39 338 1575745

E-mail: ugo.carraro@unipd.it

 

Born:                      February 23, 1943, Abano Terme (Padova), Italy

Citizenship:           Italy

Degree and Academic Positions

-       M.D. (Laurea in Medicina e Chirurgia), University of Padua, Italy -1968

-       Associate Professor of General Pathology, Faculty of Medicine, University of Padova,1983-2013

-       Principal Investigator of the Laboratory of Applied Myology of the C.N.R Institute of Neuroscience, 1983-2000

-       Acting-director of the Department of Biomedical Science -1998 to 2003;

-       Principal Investigator of the Translational Myology Lab, Department of Biomedical Science -1998 to 2013

-       Interdepartmental Research Center of Myology (cirMYO), Founder and Head 2005 - 2011

Other Professional Activities

-       1991-2019 – Founder and Editor-in-Chief of Basic Applied Myology: 1991 to date

-       Consultant of I.R.C.C.S. Ospedale San Camillo di Venezia-Lido, Italy

-        Referee for International Journals and Granting Agencies: J Cell Biol, Muscle&Nerve, Artificial Organs, J Muscle Res Cell Motility, Artificial Organs, Cell Death & Differentiation, Annals Thoracic Surgery, Acta Physiologica, The Open Rehabilitation Journal, Association Française contre les Myopathies

-       Organizer of International Conferences and Courses

-       Invited speaker and chairman in International Conferences

Main Research Interests

-       Translational Myology: Basics of muscle plasticity and their applications to medical research, in particular:

  • Functional Electrical Stimulation (FES) of denervated human muscle
  • Role of regenerative myogenesis in exercise-induced muscle damage and denervation
  • Reconstruction, neurotization and artificial synaptogenesis of ablated skeletal muscle
  • Analyses in muscle atrophy and apoptosis of role of Cytokines and Myokines by invasive and non-invasive samplings

 

Achievments and expertises

Prof. Ugo Carraro is a world-class leader in molecular and structural analyses of skeletal muscle. He developed bi-dimensional gel electrophoresis for myosin light chains, in particular the embryonic isoform, and was the first to separate human myosin heavy chain isoforms.

He discovered the long-term potential of denervated muscle to survive denervation by non-compensatory myofiber regeneration.

Prof. Carraro was Associate Professor of General Pathology at the Faculty of Medicine of the University of Padova, from 1983 to 2013. Editor-in-Chief of The European Journal of Translational Myology since 1991, he founded and chaired from 2005 to 2011 Interdepartmental Research Center of Myology (CIR-Myo) of the University of Padova. CIR-Myo continue to join scientists and clinicians of the Departments of Biology, Biomedical Sciences, Neuroscience, Medicine and Surgical Sciences, Physical Medicine and Rehabilitation and Experimental & Clinical Veterinary Sciences.

In collaboration with international partners, in particular the Ludwig Boltzmann Institute of Electrostimulation and Physical Rehabilitation of the Wilheminenspital, Vienna, Austria, CIR-Myo scientists and clinicians developed and implemented the expertise and facilities to maintain and extend in Interreg IVa a world-unique BIO-BANK of human skeletal muscle biopsies harvested from upper motor neuron and lower motor neuron denervated patients and related animal research, young and senior sportsmen, healthy and diseased elderly persons before and during recovery by new therapies and rehabilitation strategies. In particular, muscle biopsies were harvested from patients affected with spinal cord injury and severe leg trauma, osteoarthropathies and rheumatic autoimmune diseases, and cancer.

CIR-Myo is developing also new imaging methods for functional monitoring of human skeletal muscles from patients suffering with permanent and transient muscle denervation. The collaboration with the Dr. Kern’s Vienna Group resulted in new knowledge and clinical validation of rehabilitation strategies for permanently denervated human muscles using home-based Functional Electrical Stimulation (FES). Thus, a world unique human muscle biopsies DATA-BASE of structural and molecular data obtained by histology, histo- and immuno-chemistry, electron microscopy and genomic/proteomic approaches is available to compare new rehabilitation strategies against standard clinical methods.

Carraro’s Lab matured expertises working on different aspects of muscle biology and pathology, including spinal cord injuries, aging, apoptosis, and muscle regeneration. This full set of methods and expertise are uniquely present at the CIR-Myo of Padova University, and well documented by a list of original results published in leading Journals of the different research fields.

Now Professor Carraro is validating NON-INVASIVE BLOOD ANALYSES to monitor Cytokines (anti- and pro- Inflammatory) and Myokines by saliva and sweat samplings, a very promising approach that will increase acceptability of sampling by volunteering persons and frequency of sampling, a key factor to evaluate the many very transient effects of trainings and rehabilitations in early aging and aging.

Publications

PUBMED April 12, 2020: Ugo Carraro 1973 - 2019 - References: 156 - Citations > 3000 –

h-index 44;  h-index 37, excluding self-citations

List of 10 recent publications 2020-2016

  1. Ricciardi C, Edmunds KJ, Recenti M, Sigurdsson S, Gudnason V, Carraro U, Gargiulo P. Assessing cardiovascular risks from a mid-thigh CT image: a tree-based machine learning approach using radiodensitometric distributions. Sci Rep. 2020 Feb 18;10(1):2863. doi: 10.1038/s41598-020-59873-9. PMID: 32071412
  2. Carraro U. 2020PMD, 30-years of Translational Mobility Medicine at the time of COVID-19 outbreak: Last-minute forewords from the editor. Eur J Transl Myol 2020;30:8966. Doi 10.4081/ejtm.2019.8966.
  3. Albertin G, Ravara B, Kern H, Hofer C, Loefler S, Jurecka W, Guidolin D, Rambaldo A, Porzionato A, De Caro R, Zampieri S, Pond A, Alaibac M, Carraro U. Two-years of home based functional electrical stimulation recovers epidermis from atrophy and flattening after years of complete Conus-Cauda Syndrome. Medicine (Baltimore). 2019 Dec;98(52):e18509. doi: 10.1097/MD.0000000000018509. PMID: 31876739.
  4. Kern H, Gargiulo P, Pond A, Albertin G, Marcante A, Carraro U. To Reverse Atrophy of Human Muscles in Complete SCI Lower Motor Neuron Denervation by Home-Based Functional Electrical Stimulation. Adv Exp Med Biol. 2018;1088:585-591. doi: 10.1007/978-981-13-1435-3_27.
  5. Carraro U, Gava K, Baba A, Marcante A, Piccione F. To Contrast and Reverse Skeletal Muscle Atrophy by Full-Body In-Bed Gym, a Mandatory Lifestyle for Older Olds and Borderline Mobility-Impaired Persons. Adv Exp Med Biol. 2018;1088:549-560. doi: 10.1007/978-981-13-1435-3_25. Review.
  6. Carraro U. Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial - Chapter I - Foreword. Eur J Transl Myol. 2018 Feb 20;28(1):7363. doi: 10.4081/ejtm.2018.7363. eCollection 2018 Jan 12.
  7. Mosole S, Zampieri S, Furlan S, Carraro U, Löefler S, Kern H, Volpe P, Nori A. Effects of Electrical Stimulation on Skeletal Muscle of Old Sedentary People. Gerontol Geriatr Med. 2018 Apr 10;4:2333721418768998. doi: 10.1177/2333721418768998. eCollection 2018 Jan-Dec.
  8. Edmunds K, Gíslason M, Sigurðsson S, Guðnason V, Harris T, Carraro U, Gargiulo P. Advanced quantitative methods in correlating sarcopenic muscle degeneration with lower extremity function biometrics and comorbidities. PLoS One. 2018 Mar 7;13(3):e0193241. doi: 10.1371/journal.pone.0193241. eCollection 2018.
  9. Atrophy, ultra-structural disorders, severe atrophy and degeneration of denervated human muscle in SCI and Kern H, Hofer C, Loefler S, Zampieri S, Gargiulo P, Baba A, Marcante A, Piccione F, Pond A, Carraro U. Aging. Implications for their recovery by Functional Electrical Stimulation, updated 2017. Neurol Res. 2017 Jul;39(7):660-666. doi: 10.1080/01616412.2017.1314906. Epub 2017 Apr 13. Review.
  10. Edmunds KJ, Árnadóttir Í, Gíslason MK, Carraro U, Gargiulo P. Nonlinear Trimodal Regression Analysis of Radiodensitometric Distributions to Quantify Sarcopenic and Sequelae Muscle Degeneration. Comput Math Methods Med. 2016;2016:8932950. doi: 10.1155/2016/8932950. Epub 2016 Dec 27.

 

How to Cite

Carraro, U., Alberty, M. S., Anton, S., Barbieri, E., Bersch, I., Blaauw, B., Bosco, G., Forni, R., Ganassi, M., Gargiulo, P., Gentil, P., Gorgey, A. S., Leeuwenburgh, C., Maccarone, M. C., Martini, A., Masiero, S., Mayr, W., Messina, G., Morra, A., Narici, M., Ohlendieck, K., Perrin, P., Pond, A., Quadrelli, M., Rosati, R., Sestili, P., Smeriglio, P., Sweeney, H. L., Tavian, D., & Volk, G. F. (2024). Mobility Medicine: A call to unify hyper-fragmented specialties by abstracts sent to 2025Pdm3, and typescripts to Ejtm3, and <i>Diagnostics</i>. European Journal of Translational Myology. https://doi.org/10.4081/ejtm.2024.13432
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