https://doi.org/10.4081/ejtm.2024.13161
Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis
Submitted: 25 September 2024
Accepted: 26 September 2024
Published: 15 November 2024
Accepted: 26 September 2024
Abstract Views: 570
PDF: 214
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Surface Functional Electrical Stimulation (FES) is a well-studied intervention for multiple muscular disorders. However, it is still controversially discussed as a complementary therapy for complete facial paralysis. The aim of this intervention is to test a daily home-based ES concept as a pilot study regarding safety, feasibility, and effects on facial functionality and symmetry. In a prospective single-centre pilot study, 10 patients (median 61 years, denervation 130 d) with complete peripheral facial paralysis performed home-based FES of the affected lateral mouth region Stimulation parameters, facial paralysis scores and standardised photographs were assessed in monthly follow-ups. No serious adverse events appeared. Stimulation parameters could be constantly increased indicating effective muscle training while subjectively perceived functionality of the face improved. Thus, smile angle of the paralysed side improved as well. FES is a safe therapy model for application in facial nerve paralysis patients. A feasible stimulation protocol could be applied, which improved the functionality and symmetry of the stimulated facial region. A future controlled, randomised and double-blind follow-up study is needed to investigate these initial results in a further evolved replicable setting.
Doucet BM, Lam A, Griffin L. Neuromuscular electrical stimulation for skeletal muscle function. Yale J Biol Med 2012;85:201-15.
Bersch I, Fridén J. Electrical stimulation alters muscle morphological properties in denervated upper limb muscles. EBioMedicine 2021;74:103737.
DOI: https://doi.org/10.1016/j.ebiom.2021.103737
Kern H, Salmons S, Mayr W, et al. Recovery of long-term denervated human muscles induced by electrical stimulation. Muscle & Nerve 2005;31:98-101.
DOI: https://doi.org/10.1002/mus.20149
Kern H, Rossini K, Carraro U, et al. Muscle biopsies show that FES of denervated muscles reverses human muscle degeneration from permanent spinal motoneuron lesion. J Rehabil Res Dev 2005;42:43-53.
DOI: https://doi.org/10.1682/JRRD.2004.05.0061
Kern H, Carraro U. Home-based functional electrical stimulation of human permanent denervated muscles: a narrative review on diagnostics, managements, results and byproducts revisited 2020. Diagnostics (Basel) 2020;10:529.
DOI: https://doi.org/10.3390/diagnostics10080529
Marquez-Chin C, Popovic MR. Functional electrical stimulation therapy for restoration of motor function after spinal cord injury and stroke: a review. Biomed Eng Online 2020;19:34.
DOI: https://doi.org/10.1186/s12938-020-00773-4
Wang L, Fan W, Yu C, et al. Clinical effects of electrical stimulation therapy on lumbar disc herniation-induced sciatica and its influence on peripheral ROS level. J Musculoskelet Neuronal Interact 2018;18:393-8.
Smith AD, Prokopiusova T, Jones R, et al. Functional electrical stimulation for foot drop in people with multiple sclerosis: The relevance and importance of addressing quality of movement. Mult Scler 2021;27:653-60.
DOI: https://doi.org/10.1177/1352458520923958
Mueller AH, Pototschnig C. Recurrent Laryngeal Nerve Stimulator. Otolaryngol Clin North Am 2020;53:145-56.
DOI: https://doi.org/10.1016/j.otc.2019.09.009
Bersch I, Mayr W. Electrical stimulation in lower motoneuron lesions, from scientific evidence to clinical practice: a successful transition. Eur J Transl Myol 2023;33:11230.
DOI: https://doi.org/10.4081/ejtm.2023.11230
Guerreschi P, Labbé D. Sequelae of facial palsy: a comprehensive treatment. plastic and reconstructive surgery 2019;144:682e-92e.
DOI: https://doi.org/10.1097/PRS.0000000000006079
Dobel C, Miltner WHR, Witte OW, et al. Emotionale Auswirkungen einer Fazialisparese. Laryngorhinootologie 2013;92:9-23.
DOI: https://doi.org/10.1055/s-0032-1327624
Strobelt L, Kuttenreich A-M, Volk GF, et al. Oral health and oral health-related quality of life in patients with chronic peripheral facial nerve palsy with synkineses—A case-control-study. PLOS ONE 2022;17:e0276152.
DOI: https://doi.org/10.1371/journal.pone.0276152
Tuncay F, Borman P, Taşer B, et al. Role of electrical stimulation added to conventional therapy in patients with idiopathic facial (Bell) palsy. Am J Phys Med Rehabil 2015;94:222-8.
DOI: https://doi.org/10.1097/PHM.0000000000000171
Mäkelä E, Venesvirta H, Ilves M, et al. Facial muscle reanimation by transcutaneous electrical stimulation for peripheral facial nerve palsy. J Med Eng Technol 2019;43:155-64.
DOI: https://doi.org/10.1080/03091902.2019.1637470
Choi JB. Effect of neuromuscular electrical stimulation on facial muscle strength and oral function in stroke patients with facial palsy. J Phys Ther Sci 2016;28:2541-43.
DOI: https://doi.org/10.1589/jpts.28.2541
Bradley MB. The effect of participating in a functional electrical stimulation exercise program on affect in people with spinal cord injuries. Arch Phys Med Rehabil 1994;75:676-9.
DOI: https://doi.org/10.1016/0003-9993(94)90193-7
Diels HJ. Facial paralysis: is there a role for a therapist? Facial Plast Surg 2000;16:361-4.
DOI: https://doi.org/10.1055/s-2000-15546
Yoo MC, Kim JH, Kim YJ, et al. Effects of electrical stimulation on facial paralysis recovery after facial nerve injury: a review on preclinical and clinical studies. J Clin Med 2023;12:4133.
DOI: https://doi.org/10.3390/jcm12124133
Puls WC, Jarvis JC, Ruck A, et al. Surface electrical stimulation for facial paralysis is not harmful. Muscle Nerve 2020;61:347-53.
DOI: https://doi.org/10.1002/mus.26784
Burelo-Peregrino EG, Salas-Magaña M, Arias-Vázquez PI, et al. Efficacy of electrotherapy in Bell's palsy treatment: A systematic review. J Back Musculoskelet Rehabil 2020;33:865-74.
DOI: https://doi.org/10.3233/BMR-171031
Boncompagni S, Kern H, Rossini K, et al. Structural differentiation of skeletal muscle fibers in the absence of innervation in humans. Proc Natl Acad Sci U S A 2007;104:19339-44.
DOI: https://doi.org/10.1073/pnas.0709061104
Sajer S, Guardiero GS, Scicchitano BM. Myokines in home-based functional electrical stimulation-induced recovery of skeletal muscle in elderly and permanent denervation. Eur J Transl Myol 2018;28:7905.
DOI: https://doi.org/10.4081/ejtm.2018.7905
Guntinas-Lichius O, Volk GF, Olsen KD, et al. Facial nerve electrodiagnostics for patients with facial palsy: a clinical practice guideline. Eur Arch Otorhinolaryngol 2020;277:1855-74.
DOI: https://doi.org/10.1007/s00405-020-05949-1
Geißler K, Guntinas-Lichius O, Fabian Volk G. [Needle electromyography of facial muscles]. Laryngorhinootologie 2016;95:528-9.
DOI: https://doi.org/10.1055/s-0042-110277
Meincke G, Krauß J, Geitner M, et al. Functional electrical stimulation decelerates denervated facial muscle atrophy in facial nerve paralysis patients: sonographic quantification. Eur J Transl Myol 2024; doi: 10.4081/ejtm.2024.13162
DOI: https://doi.org/10.4081/ejtm.2024.13162
Ross BG, Fradet G, Nedzelski JM. Development of a sensitive clinical facial grading system. Otolaryngol Head Neck Surg 1996;114:380-6.
DOI: https://doi.org/10.1016/S0194-59989670206-1
Neumann T, Lorenz A, Volk GF, et al. [Validation of the German Version of the Sunnybrook Facial Grading System]. Laryngo- rhino- otologie 2017;96:168-74.
DOI: https://doi.org/10.1055/s-0042-111512
Kahn JB, Gliklich RE, Boyev KP, et al. Validation of a patient-graded instrument for facial nerve paralysis: the FaCE scale. Laryngoscope 2001;111:387-98.
DOI: https://doi.org/10.1097/00005537-200103000-00005
Ho AL, Scott AM, Klassen AF, et al. Measuring quality of life and patient satisfaction in facial paralysis patients: a systematic review of patient-reported outcome measures. Plast Reconstr Surg 2012;130:91-9.
DOI: https://doi.org/10.1097/PRS.0b013e318254b08d
VanSwearingen JM, Brach JS. The Facial Disability Index: reliability and validity of a disability assessment instrument for disorders of the facial neuromuscular system. Physical therapy 1996;76:1288-98; discussion 1298-300.
DOI: https://doi.org/10.1093/ptj/76.12.1288
Volk GF, Steigerwald F, Vitek P, et al. [Facial Disability Index and Facial Clinimetric Evaluation Scale: validation of the German versions]. Laryngorhinootologie 2015;94:163-168.
DOI: https://doi.org/10.1055/s-0034-1381999
Sauer M. Instructions for sonography of the facial muscles / Anleitung zur Sonographie der mimischen Muskulatur. Updated December 1, 2015. Acessed April 8, 2024. Available from: https://www.researchgate.net/publication/285334151_Instructions_for_sonography_of_the_facial_muscles_Anleitung_zur_Sonographie_der_mimischen_Muskulatur
Volk GF, Sauer M, Pohlmann M, et al. Reference values for dynamic facial muscle ultrasonography in adults. Muscle Nerve 2014;50:348-57.
DOI: https://doi.org/10.1002/mus.24204
Arnold D, Thielker J, Klingner CM, et al. Selective Surface Electrostimulation of the Denervated Zygomaticus Muscle. Diagnostics (Basel) 2021;11:188.
DOI: https://doi.org/10.3390/diagnostics11020188
Guarin DL, Dusseldorp J, Hadlock TA, et al. A machine learning approach for automated facial measurements in facial palsy. JAMA Facial Plastic Surgery 2018;20:335-7.
DOI: https://doi.org/10.1001/jamafacial.2018.0030
Beckmann J. Heilungsverlauf von Patienten mit akuter peripherer Fazialisparalyse unter Oberflächenelektrostimulation: eine klinische Beobachtungstudie zum Vergleich von subjektiven Klassifikationen des Schweregrads gegenüber einer automatischen euklidischen Bildanalyse [Medical Thesis]. Germany, Jena: Friedrich-Schiller University Jena; 2023.
Brüggemann AK, Mello CL, Dal Pont T, et al. Effects of Neuromuscular Electrical Stimulation During Hemodialysis on Peripheral Muscle Strength and Exercise Capacity: A Randomized Clinical Trial. Arch Phys Med Rehabil 2017;98:822-831.e821.
DOI: https://doi.org/10.1016/j.apmr.2016.12.009
Crameri RM, Weston A, Climstein M, et al. Effects of electrical stimulation-induced leg training on skeletal muscle adaptability in spinal cord injury. Scand J Med Sci Sports 2002;12:316-22.
DOI: https://doi.org/10.1034/j.1600-0838.2002.20106.x
Kim MG, Bae CR, Oh TS, et al. Reliability and Validity of emotrics in the assessment of facial palsy. J Pers Med 2023;13:1135.
DOI: https://doi.org/10.3390/jpm13071135
Mastryukova V, Arnold D, Güllmar D, et al. Can MRI quantify the volume changes of denervated facial muscles? Eur J Transl Myol 2020;30:8918.
DOI: https://doi.org/10.4081/ejtm.2019.8918
Radnót M, Follmann P. Ultrastructural changes in senile atrophy of the orbicularis oculi muscle. Am J Ophthalmol 1974;78:689-99.
DOI: https://doi.org/10.1016/S0002-9394(14)76308-1
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Krauß, J., Meincke, G., Geitner, M., Kuttenreich, A.-M., Beckmann, J., Arnold, D., Ballmaier, J., Lehmann, T., Mayr, W., Guntinas-Lichius, O., & Volk, G. F. (2024). Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis. European Journal of Translational Myology, 34(4). https://doi.org/10.4081/ejtm.2024.13161
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