https://doi.org/10.4081/ejtm.2024.12693
The time course of irisin release after an acute exercise: relevant implications for health and future experimental designs
Submitted: 30 May 2024
Accepted: 20 June 2024
Published: 1 July 2024
Accepted: 20 June 2024
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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This study aimed to analyze the acute impact of exercise on serum irisin levels in 22 young (YA, 24.6 ± 3.5 yrs) and in 12 middle-aged male adults (MA, 54.6 ± 5.7 yrs) 15 min and 24 h after an incremental cycling exercise test to exhaustion. ELISA assay was used for serum irisin detection. Circulating irisin increased significantly from baseline (9.0 ± 2.0 ng/ml) to 15 min post-exercise (10.2 ± 2.0 ng/ml, P < 0.001), but the greatest increment was detected after 24 h (13.5 ± 2.5 ng/ml, P < 0.001) reaching more than 50% of the basal release. Levels were significantly higher in YA (9.7 ± 1.7 to 11.1 ± 1.8 to 14.5 ± 2.2 ng/ml) than MA (7.6 ± 1.6 to 8.7 ± 1.5 to 11.8± 2.2 ng/ml) for all measured time-points (P < 0.05). Nevertheless, MA showed a comparable increase in serum irisin levels when compared to YA. These findings highlight the importance of acute physical exercise as a countermeasure against age-related deterioration of skeletal muscle mass and function in both YA and MA.
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How to Cite
Tommasini, E., Missaglia, S., Vago, P., Galvani, C., Pecci, C., Rampinini, E., Bosio, A., Morelli, A., Bonanomi, A., Silvestrini, A., Mordente, A., & Tavian, D. (2024). The time course of irisin release after an acute exercise: relevant implications for health and future experimental designs . European Journal of Translational Myology, 34(2). https://doi.org/10.4081/ejtm.2024.12693
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