Dirk Pette, remembered for his pioneering muscle research

Published: 22 May 2024
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Authors

It is with great sadness that we learned of the passing of Prof. Dr. Dr. h.c. Dirk Pette. He passed away suddenly and unexpectedly on June 4, 2022. Dirk was an outstanding professor of biochemistry at the University of Konstanz, Germany and an internationally renowned researcher in the field of skeletal muscle biology. His research on electrical stimulation has had a profound impact on our understanding of myofiber type specification and the enormous adaptive potential of skeletal muscle. Under Dirk's leadership, new biological questions in the field of neuromuscular biology have developed into multidisciplinary approaches using advanced physiological, cell biological, and biochemical techniques. Dirk's research laboratory was frequently visited by a large number of national and international collaborators who familiarized themselves with the technically demanding stimulation protocols and bioanalytical techniques to study the intricate details of the highly complex process of fast-to-slow muscle transitions. Importantly, fundamental studies on the physiological effects of changes in innervation patterns on muscle phenotype have provided the scientific evidence base for a variety of innovative clinical applications. The skeletal muscle research community has lost one of its leading figures and an outstanding teacher of protein biochemistry. He leaves an inspiring legacy in the field of basic and applied myology. Dirk will be missed by his colleagues and by many students of neuromuscular biology and beyond.

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Citations

Plasticity of Muscle: Proceedings of a Symposium held at the University of Konstanz, Germany, September 23–28, 1979. Edited by: Dirk Pette. Berlin, Boston: De Gruyter, 1980.
The Dynamic State of Muscle Fibers. Proceedings of the International Symposium. October 1–6, 1989, Konstanz, Federal Republic of Germany. Edited by: Dirk Pette Berlin, Boston: De Gruyter, 1990.
Pette D. The adaptive potential of skeletal muscle fibers. Can J Appl Physiol 2002;27:423-48. DOI: https://doi.org/10.1139/h02-023
Pette D, Vrbová G. Neural control of phenotypic expression in mammalian muscle fibers. Muscle Nerve 1985;8:676-89. DOI: https://doi.org/10.1002/mus.880080810
Pette D, Vrbová G. What does chronic electrical stimulation teach us about muscle plasticity? Muscle Nerve 1999;22:666-77. DOI: https://doi.org/10.1002/(SICI)1097-4598(199906)22:6<666::AID-MUS3>3.0.CO;2-Z
Pette D, Vrbová G. The Contribution of Neuromuscular Stimulation in Elucidating Muscle Plasticity Revisited. Eur J Transl Myol 2017;27:6368. DOI: https://doi.org/10.4081/ejtm.2017.6368
Pette, D. The significance of Gerta Vrbová's low-frequency stimulation experiment. Eur J Transl Myol 2021;31:9585. DOI: https://doi.org/10.4081/ejtm.2021.9585
Carraro U. Gerta Vrbová, a guide and a friend for a generation of neuro-myologists - Her scientific legacies and relations with colleagues. Eur J Transl Myol 2021;31:9670. DOI: https://doi.org/10.4081/ejtm.2021.9670
Proceedings of the 1st Vienna International Workshop on Functional Electrical Stimulation – Basics, Technology and Application. Vienna (Austria) October 19-22, 1983
Carraro U, Catani C. Isomyosin changes in direct electrical stimulation of denervated rat EDL. Proceedings of the 1st Vienna International Workshop on Functional Electrical Stimulation – Basics, Technology and Application. Vienna (Austria) October 19-22, 1983 Section 1.8.

How to Cite

Ohlendieck, K., Mayr, W., Kern, H., Reggiani, C., Fanò-Illic, G., & Carraro, U. (2024). Dirk Pette, remembered for his pioneering muscle research. European Journal of Translational Myology, 34(2). https://doi.org/10.4081/ejtm.2024.12681