https://doi.org/10.4081/ejtm.2024.12311

Vertebral bone quality score as a new tool for osteoporosis diagnosis in patients undergoing lumbosacral fusion surgery: a single center cohort study

Early Access
Submitted: 25 January 2024
Accepted: 21 June 2024
Published: 16 September 2024
Vertebral bone quality, magnetic resonance imaging, osteoporosis, osteopenia, spinal fusion surgery
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Authors

Arvin Najafi
Departement of Orthopedic Surgery, Shahid Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran, Islamic Republic of.
Ali Baradaran Bagheri
Department of Neurosurgery, Shahid Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran, Islamic Republic of.
Dorsa Hadavi
Department of Radiology, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
Aidin Mobedi
Shahid Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran, Islamic Republic of.
Salman Azarsina
Departement of Orthopedic Surgery, Shahid Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran, Islamic Republic of.
Pouria Chaghamirzayi
Pouriachaghamirzayi@yahoo.com
https://orcid.org/0000-0002-0100-1190
Clinical research development unit of Shahid Madani Hospital, Alborz University of Medical Science, Karaj, Iran, Islamic Republic of.

Osteoporosis, a common bone disorder, increases fracture and spinal surgery complications risk. This study evaluates the potential of the Magnetic Resonance Imaging (MRI)-based Vertebral Bone Quality (VBQ) score as an alternative for assessing bone density in lumbosacral fusion surgery patients. In a prospective cohort study from April 2021 to November 2022, 134 patients with lumbar degenerative diseases underwent lumbar Dual-Energy X-ray Absorptiometry (DXA) and lumbosacral non-contrast T1-weighted MRI. VBQ scores were calculated and analyzed using IBM SPSS Statistics and MedCalc software. Osteopenia/Osteoporosis patients exhibited significantly higher VBQ scores than normal bone mineral density patients (3.37 ± 0.51 vs. 2.99 ± 0.44, P<0.001). VBQ correlated significantly with lumbar DXA T scores (r value= -0.415, p<0.001). Receiver Operating Characteristic (ROC) analysis showed VBQ AUC values of 0.730 (CI 95% 0.647-0.803, P<0.001) and 0.839 (CI 95% 0.765-0.897, P<0.001) for Osteopenia/Osteoporosis and osteoporosis diagnosis, respectively. The study suggests MRI-derived VBQ scores may benefit pre-lumbosacral fusion surgery bone density assessment, potentially improving patient care and aiding osteoporosis detection in spinal surgery candidates.

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How to Cite

Najafi, A., Baradaran Bagheri, A., Hadavi, D., Mobedi, A., Azarsina, S., & Chaghamirzayi, P. (2024). Vertebral bone quality score as a new tool for osteoporosis diagnosis in patients undergoing lumbosacral fusion surgery: a single center cohort study. European Journal of Translational Myology. https://doi.org/10.4081/ejtm.2024.12311
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