Transcutaneous tibial neurostimulation and Solifenacin in urgent incontinence of postmenopausal women

Submitted: 5 April 2023
Accepted: 24 April 2023
Published: 20 June 2023
Abstract Views: 526
PDF: 374
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Symptoms of overactive bladder syndrome (OAB), including urinary incontinence, affect a person's quality of life and cause many personal, social and economic problems. Patients were randomly divided into three groups and received transcutaneous tibial nerve stimulation (cTTNS) with fixed parameters or with variable parameters (vTTNS) and Solifenacin drug. The main outcomes including quality of life questionnaire and OAB score and other secondary outcomes were evaluated before and after treatment for 6 weeks. ANOVA test did not show any significant difference between the three groups in quality of life score (p=0.672), OAB symptom score (p=0.159) and incontinence severity (p=0.422). The t-test demonstrated that the post treatment average quality of life score, OAB score, and incontinence severity were significantly different when compared with before treatment in all three groups (p < 0.05). All three methods were effective in treating symptoms of OAB. However, based on the clinical symptoms, cTTNS is recommended as a preferred and acceptable and safe strategy for the treatment of OAB in women over 50 years old.

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Irwin DE, Milsom I, Chancellor MB, Kopp Z, Guan Z. Dynamic progression of overactive bladder and urinary incontinence symptoms: a systematic review. Eur Urol. 2010 Oct;58(4):532-43. Epub 2010 Jun 15. PMID: 20573443. DOI: https://doi.org/10.1016/j.eururo.2010.06.007
Irwin DE, Milsom I, Hunskaar S, Reilly K, Kopp Z, Herschorn S, Coyne K, Kelleher C, Hampel C, Artibani W, Abrams P. Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol. 2006 Dec;50(6):1306-14; discussion 1314-5. Epub 2006 Oct 2. PMID: 17049716.
Hu TW, Wagner TH, Bentkover JD, Leblanc K, Zhou SZ, Hunt T. Costs of urinary incontinence and overactive bladder in the United States: a comparative study. Urology. 2004 Mar;63(3):461-5. PMID: 15028438. DOI: https://doi.org/10.1016/j.urology.2003.10.037
Irwin DE, Kopp ZS, Agatep B, Milsom I, Abrams P. Worldwide prevalence estimates of lower urinary tract symptoms, overactive bladder, urinary incontinence and bladder outlet obstruction. BJU Int. 2011 Oct;108(7):1132-8. Epub 2011 Jan 13. PMID: 21231991. DOI: https://doi.org/10.1111/j.1464-410X.2010.09993.x
Pakgohar M SS, Vasegh Rahimpor SF, Kazemneghad A. Investigating the quality of life of postmenopausal women with urinary incontinence: a cross-sectional study. Payesh. 2013;13(1):73-81. URL: http://payeshjournal.ir/article-1-326-en.html
Coyne KS, Wein A, Nicholson S, Kvasz M, Chen CI, Milsom I. Comorbidities and personal burden of urgency urinary incontinence: a systematic review. Int J Clin Pract. 2013 Oct;67(10):1015-33. PMID: 24073974. DOI: https://doi.org/10.1111/ijcp.12164
Lightner DJ, Gomelsky A, Souter L, Vasavada SP. Diagnosis and Treatment of Overactive Bladder (Non-Neurogenic) in Adults: AUA/SUFU Guideline Amendment 2019. J Urol. 2019 Sep;202(3):558-563. Epub 2019 Aug 8. PMID: 31039103. DOI: https://doi.org/10.1097/JU.0000000000000309
Vecchioli-Scaldazza C, Morosetti C, Berouz A, Giannubilo W, Ferrara V. Solifenacin succinate versus percutaneous tibial nerve stimulation in women with overactive bladder syndrome: results of a randomized controlled crossover study. Gynecol Obstet Invest. 2013;75(4):230-4. Epub 2013 Mar 28. PMID: 23548260. DOI: https://doi.org/10.1159/000350216
Govier FE, Litwiller S, Nitti V, Kreder KJ Jr, Rosenblatt P. Percutaneous afferent neuromodulation for the refractory overactive bladder: results of a multicenter study. J Urol. 2001 Apr;165(4):1193-8. PMID: 11257669. DOI: https://doi.org/10.1016/S0022-5347(05)66469-5
Ramírez-García I, Blanco-Ratto L, Kauffmann S, Carralero-Martínez A, Sánchez E. Efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome: Randomized control trial. Neurourol Urodyn. 2019 Jan;38(1):261-268. Epub 2018 Oct 12. PMID: 30311692. DOI: https://doi.org/10.1002/nau.23843
Vandoninck V, Van Balken MR, Finazzi Agró E, Petta F, Caltagirone C, Heesakkers JP, Kiemeney LA, Debruyne FM, Bemelmans BL. Posterior tibial nerve stimulation in the treatment of urge incontinence. Neurourol Urodyn. 2003;22(1):17-23. PMID: 12478596. DOI: https://doi.org/10.1002/nau.10036
Nojomi M, Baharvand P, Moradi Lakeh M, Patrick DL. Incontinence quality of life questionnaire (I-QOL): translation and validation study of the Iranian version. Int Urogynecol J Pelvic Floor Dysfunct. 2009 May;20(5):575-9. Epub 2009 Feb 10. PMID: 19209375. DOI: https://doi.org/10.1007/s00192-009-0808-y
Hakimi S, Dargahi R, Asl NM, Ranjbar M, Mohammadi M, Nikan F, Nedale H. Iranian Version of Overactive Bladder Symptom Scale: A Methodological Study. Cres J Med Biol Sci. 2018;5(4):70-366. Link to: https://www.cjmb.org /text.php?id=239 .
Homma Y, Yoshida M, Seki N, Yokoyama O, Kakizaki H, Gotoh M, Yamanishi T, Yamaguchi O, Takeda M, Nishizawa O. Symptom assessment tool for overactive bladder syndrome--overactive bladder symptom score. Urology. 2006 Aug;68(2):318-23. PMID: 16904444. DOI: https://doi.org/10.1016/j.urology.2006.02.042
Kubota Y, Kojima Y, Shibata Y, Imura M, Kohri K, Sasaki S. Correlation between improvements in Overactive Bladder Symptom Score and health-related quality of life questionnaires in overactive bladder patients treated with an antimuscarinic drug. Neurourol Urodyn. 2011 Sep;30(7):1309-14. Epub 2011 May 10. PMID: 21560155. DOI: https://doi.org/10.1002/nau.21065
- Vecchioli-Scaldazza C, Morosetti C. Effectiveness and durability of solifenacin versus percutaneous tibial nerve stimulation versus their combination for the treatment of women with overactive bladder syndrome: a randomized controlled study with a follow-up of ten months. Int Braz J Urol. 2018 Jan-Feb;44(1):102-108. PMID: 29064651; PMCID: PMC5815539. DOI: https://doi.org/10.1590/s1677-5538.ibju.2016.0611
Radinmehr H, Tabatabae A, Alemi M. The effect of transcutaneous posterior tibial nerve stimulation on the overactive bladder in a child: a case study. Middle East J Rehabil Health Stud. 2021; 8(1):e106014. DOI: https://doi.org/10.5812/mejrh.106014
de Wall LL, Heesakkers JP. Effectiveness of percutaneous tibial nerve stimulation in the treatment of overactive bladder syndrome. Res Rep Urol. 2017 Aug 14;9:145-157. PMID: 28861404; PMCID: PMC5565382. DOI: https://doi.org/10.2147/RRU.S124981
Ramírez-García I, Blanco-Ratto L, Kauffmann S, Carralero-Martínez A, Sánchez E. Efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome: Randomized control trial. Neurourol Urodyn. 2019 Jan;38(1):261-268. Epub 2018 Oct 12. PMID: 30311692. DOI: https://doi.org/10.1002/nau.23843
Sayner AM, Rogers F, Tran J, Jovanovic E, Henningham L, Nahon I. Transcutaneous Tibial Nerve Stimulation in the Management of Overactive Bladder: A Scoping Review. Neuromodulation. 2022 Dec;25(8):1086-1096. Epub 2022 Jun 8. PMID: 35688702. DOI: https://doi.org/10.1016/j.neurom.2022.04.034
Booth J, Connelly L, Dickson S, Duncan F, Lawrence M. The effectiveness of transcutaneous tibial nerve stimulation (TTNS) for adults with overactive bladder syndrome: A systematic review. Neurourol Urodyn. 2018 Feb;37(2):528-541. Epub 2017 Jul 21. PMID: 28731583. DOI: https://doi.org/10.1002/nau.23351
Zhang Y, Wang S, Zu S, Zhang C. Transcutaneous electrical nerve stimulation and solifenacin succinate versus solifenacin succinate alone for treatment of overactive bladder syndrome: A double-blind randomized controlled study. PLoS One. 2021 Jun 23;16(6):e0253040. PMID: 34161360; PMCID: PMC8221460. DOI: https://doi.org/10.1371/journal.pone.0253040

How to Cite

Radinmehr, H., Radnia, N., Tabatabaei, A., Asadi, M. R., Rahbar, S., Talimkhani, A., Irani, A. D., & Hajvalie, G. R. (2023). Transcutaneous tibial neurostimulation and Solifenacin in urgent incontinence of postmenopausal women. European Journal of Translational Myology, 33(2). https://doi.org/10.4081/ejtm.2023.11358