https://doi.org/10.4081/ejtm.2022.10808

Promethazine hydrochloride reduces children’s agitation during ocular examination for trauma

Vol. 33 No. 1 (2023)
Submitted: 21 August 2022
Accepted: 26 August 2022
Published: 8 September 2022
Examination, ocular, promethazine hydrochloride, trauma
Abstract Views: 1137
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Authors

Zahra Ghiasi
Department of Psychiatry and Clinical Psychology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran, Islamic Republic of.
Mohammad Hosein Validad
Department of Ophthalmology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran, Islamic Republic of.
Shokoufeh Mogharabi Ostadkelayeh
Faculty of Nursing, Iranshahr Branch, Islamic Azad University, Iranshahr, Iran, Islamic Republic of.
Sakineh Mazloom
Department of Nursing, Zahedan Branch, Islamic Azad University, Zahedan, Iran, Islamic Republic of.
Jamshid Ordoni Avval
Department of Anesthesiology and Critical Care Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran, Islamic Republic of.
Mohammadreza Moshari
Department of Anesthesiology and Critical Care Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of.
Mastaneh Dahi
Department of Anesthesiology and Critical Care Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of.
Mohammad Gharehbeglou
Department of Anesthesiology and Critical Care Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran , Iran, Islamic Republic of.
Mohsen Khosravi
dr_khosravi2016@yahoo.com
https://orcid.org/0000-0003-2970-6309
Department of Psychiatry and Clinical Psychology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran, Islamic Republic of.

Examination and intervention are always the causes of agitation, anxiety, and fear in children’s lives. This study aimed to investigate the effectiveness of promethazine hydrochloride in reducing children’s agitation during the ocular examination for trauma. In this interventional-clinical trial study, a total of 62 children referred to Al-Zahra Ophthalmology Hospital in Zahedan, Iran, were evaluated in two matched groups (case (n = 31) and control (n = 31)) for an initial examination of ocular trauma. Finally, the intervention was performed (giving placebo or promethazine hydrochloride cough syrup 20 minutes before the initial ocular examination at 0.5 mg/kg), and the demographic information form and researcher-made questionnaire modeled on the Cohen-Mansfield Agitation Inventory (CMAI) were completed. The obtained results revealed that the mean scores of physical/aggressive behaviors (p ˂ 0.001), physical/nonaggressive behaviors (p = 0.013), verbal/aggressive behaviors (p ˂ 0.001), and hiding behaviors (p ˂ 0.001) were significantly lower in the promethazine hydrochloride-receiving group than the placebo group. These findings demonstrated that promethazine hydrochloride cough syrup facilitated the examination among the pediatric patients who suffered from traumatic ocular injuries. However, further studies in this field need to be carried out through randomized controlled trials.

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How to Cite

Ghiasi, Z., Validad, M. H., Ostadkelayeh, S. M., Mazloom, S., Avval, J. O., Moshari, M., Dahi, M., Gharehbeglou, M., & Khosravi, M. (2022). Promethazine hydrochloride reduces children’s agitation during ocular examination for trauma. European Journal of Translational Myology, 33(1). https://doi.org/10.4081/ejtm.2022.10808
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