https://doi.org/10.4081/ejtm.2022.10672
A retrospective study comparing oral health in cancer patients and healthy people
Submitted: 13 June 2022
Accepted: 27 June 2022
Published: 29 August 2022
Accepted: 27 June 2022
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The purpose of this study was to investigate the relationship between oral and dental health in cancer patients and control group, which was conducted in Tabriz Shahid Gazi hospital. A researchers-made and validated questionnaire including oral and dental health criteria, was filled by the cancer patients (201 cases) and healthy controls (199 cases). Then, the results of the study were analyzed by SPSS software, and reported as Odds ratios (95 % confidence intervals) in tow groups. The results indicate that comparison of filled tooth, tooth extraction, dental caries, and gingival problems including bleeding, gum surgery and inflammation in cancer and controls were significantly meaningful. However, the comparison between the two groups was not significant in terms of the type of the tooth (natural or denture) and the number of daily toothbrushes, but they were considered as risk factors due to statistical results. Environmental factors, and especially oral hygiene, can play an important role in the incidence of different cancers. Among these, the type of oral microorganisms, and their overgrowth and released antigens should be studied further in the emergence of different kinds of cancer in humans.
Brownell I, Ramírez-Valle F, Sanchez M, Prystowsky S. Evidence for mycobacteria in sarcoidosis. Am J Respir Cell Mol Biol. 2011 Nov;45(5):899-905. Epub 2011 Jun 9.
DOI: https://doi.org/10.1165/rcmb.2010-0433TR
Cantwell AR Jr. Variably acid-fast bacteria in a rare case of coexistent malignant lymphoma and cutaneous sarcoid-like granulomas. Int J Dermatol. 1982 Mar;21(2):99-106.
DOI: https://doi.org/10.1111/j.1365-4362.1982.tb00512.x
Cantwell AR: The Russell body - the forgotten clue to the bacterial cause of cancer. JOIMR 2003; 1(6):1. https://www.semanticscholar.org/paper /THE-RUSSELL-BODY-%3A-THE-FORGOTTEN-CLUE-TO-THE-CAUSE-Body/666735ac952b1e680ac80e770d639b81c4cd7e2c
Cantwell AR Jr: Pleomorphic bacteria as a cause of hodgkin’s disease (Hodgkin’s lymphoma): A Review of the Literature. JOIMR 2006; 4(1):1 https://www.semanticscholar.org/paper/Pleomorphic-Bacteria-As-A-Cause-Of-Hodgkin%27s-Cantwell-D./d5b851d2a32233bb3f4f30c55307e 28464542 da2
Kåhrström CT, Pariente N, Weiss U. Intestinal microbiota in health and disease. Nature. 2016 Jul 7;535(7610):47.
DOI: https://doi.org/10.1038/535047a
Kerr AR. The oral microbiome and cancer. J Dent Hyg. 2015 Feb;89 Suppl 1:20-3.
Sekirov I, Russell SL, Antunes LC, Finlay BB. Gut microbiota in health and disease. Physiol Rev. 2010 Jul;90(3):859-904.
DOI: https://doi.org/10.1152/physrev.00045.2009
Meyer MS, Joshipura K, Giovannucci E, Michaud DS. A review of the relationship between tooth loss, periodontal disease, and cancer. Cancer Causes Control. 2008 Nov;19(9):895-907. Epub 2008 May 14.
DOI: https://doi.org/10.1007/s10552-008-9163-4
Fitzpatrick SG, Katz J. The association between periodontal disease and cancer: a review of the literature. J Dent. 2010 Feb;38(2):83-95. Epub 2009 Nov 4. PMID: 19895866.
DOI: https://doi.org/10.1016/j.jdent.2009.10.007
D'Souza G, Kreimer AR, Viscidi R, Pawlita M, Fakhry C, Koch WM, Westra WH, Gillison ML. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007 May 10;356(19):1944-56.
DOI: https://doi.org/10.1056/NEJMoa065497
Purnima S. Kumar. Oral microbiota and systemic disease. Anaerobe 2013;24:90–93.
DOI: https://doi.org/10.1016/j.anaerobe.2013.09.010
Skorupka W, Zurek K, Kokot T, Nowakowska-Zajdel E, Fatyga E, Niedworok E, Muc-Wierzgoń M. Assessment of oral hygiene in adults. Cent Eur J Public Health. 2012 Sep;20(3):233-6.
Arigbede AO, Babatope BO, Bamidele MK. Periodontitis and systemic diseases: A literature review. J Indian Soc Periodontol 2012; 16:487–491.
DOI: https://doi.org/10.4103/0972-124X.106878
Seymour RA. Is oral health a risk for malignant disease? Dent Update. 2010 Jun;37(5):279-80, 282-3.
DOI: https://doi.org/10.12968/denu.2010.37.5.279
Guerrero-Preston R, Godoy-Vitorino F, Jedlicka A, Rodríguez-Hilario A, González H, Bondy J etal. 16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment. Oncotarget 2016; (32):51320-51334.
DOI: https://doi.org/10.18632/oncotarget.9710
Flynn KJ, Baxter NT, Schloss PD. Metabolic and community synergy of oral bacteria in colorectal cancer. mSphere 2016;1(3):e00102-16.
DOI: https://doi.org/10.1128/mSphere.00102-16
Jiyoung A, Stephanie S, Richard B.Hayes. Periodontal disease, Porphyromonas gingivalis serum antibody levels and orodigestive cancer mortality. Carcinogenesis 2012; 33(5):1055–1058,
DOI: https://doi.org/10.1093/carcin/bgs112
Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, Queiroz EL, Nightingale K, Kerr AR, DeLacure MD, Veeramachaneni R, Olshen AB, Albertson DG. Changes in abundance of oral microbiota associated with oral cancer. PLoS One. 2014 Jun 2;9(6):e98741. Erratum in: PLoS One. 2014;9(8):e106297. Muy-Teck The [removed].
Pushalkar S, Ji X, Li Y, Estilo C, Yegnanarayana R, Singh B, Li X, Saxena D. Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma. BMC Microbiol. 2012 Jul 20;12:144.
DOI: https://doi.org/10.1186/1471-2180-12-144
Kadkhodazadeh M, Amid R, Zarnegarnia P, Mollaverdi F, Safi Y, Eslami M. Comparative assessment of a standard oral hygiene regimen with and without mouthwash and related clinical findings over a 14-day period. J Periodontol Implant Dent 2015;7(1):21–25.
DOI: https://doi.org/10.15171/jpid.2015.004
Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, et al. Changes in abundance of oral microbiota associated with oral cancer. PLoS ONE 2014; 9(6): e98741.
DOI: https://doi.org/10.1371/journal.pone.0098741
Taghipour A, Current status of cancer research, diagnosis and therapy in iran-2015: An Update. Cancer Press. 2016. 2(1): 1-4.
DOI: https://doi.org/10.15562/tcp.8
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. Epub 2018 Sep 12.m.
DOI: https://doi.org/10.3322/caac.21492
Torre LA, Siegel RL, Ward EM, Jemal A. Global cancer incidence and mortality rates and trends-an update. Cancer Epidemiology Biomarkers & Prev. 2015;
DOI: https://doi.org/10.1158/1055-9965.EPI-15-0578
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D.Global cancer statistics. CA Cancer J Clin. 2011; 61(2):69-90. Epub 2011 Feb 4.
DOI: https://doi.org/10.3322/caac.20107
Nicolatou-Galitis O, Sarri T, Bowen J, Di Palma M, Kouloulias VE, Niscola P, Riesenbeck D, Stokman M, Tissing W, Yeoh E, Elad S, Lalla RV; Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO). Systematic review of amifostine for the management of oral mucositis in cancer patients. Support Care Cancer. 2013 Jan;21(1):357-64. Epub 2012 Oct 3.
DOI: https://doi.org/10.1007/s00520-012-1613-6
Djuric M, Hillier-Kolarov V, Belic A, Jankovic L. Mucositis prevention by improved dental care in acute leukemia patients. Support Care Cancer. 2006 Feb;14(2):137-46. Epub 2005 Jul 22.
DOI: https://doi.org/10.1007/s00520-005-0867-7
Güneri P, Cankaya H, Yavuzer A, Güneri EA, Erişen L, Ozkul D, El SN, Karakaya S, Arican A, Boyacioğlu H. Primary oral cancer in a Turkish population sample: association with sociodemographic features, smoking, alcohol, diet and dentition. Oral Oncol. 2005 Nov;41(10):1005-12. Epub 2005 Aug 31.
DOI: https://doi.org/10.1016/j.oraloncology.2005.06.002
Fernandes LL, Torres SR, Garnica M, de Souza Gonçalves L, Junior AS, de Vasconcellos ÁC, Cavalcanti W, Maiolino A, de Barros Torres MC. Oral status of patients submitted to autologous hematopoietic stem cell transplantation. Support Care Cancer. 2014 Jan;22(1):15-21. Epub 2013 Aug 24. PMID: 23975228.
DOI: https://doi.org/10.1007/s00520-013-1940-2
Lawrence M, Aleid W, McKechnie A. Access to dental services for head and neck cancer patients. Br J Oral Maxillofac Surg. 2013 Jul;51(5):404-7. Epub 2012 Nov 3.
DOI: https://doi.org/10.1016/j.bjoms.2012.10.004
Hong CH, Napeñas JJ, Hodgson BD, Stokman MA, Mathers-Stauffer V, Elting LS, Spijkervet FK, Brennan MT; Dental Disease Section, Oral Care Study Group, Multi-national Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of dental disease in patients undergoing cancer therapy. Support Care Cancer. 2010 Aug;18(8):1007-21. Epub 2010 May 7.
DOI: https://doi.org/10.1007/s00520-010-0873-2
Skorupka W, Zurek K, Kokot T, Nowakowska-Zajdel E, Fatyga E, Niedworok E, Muc-Wierzgoń M. Assessment of oral hygiene in adults. Cent Eur J Public Health. 2012 Sep;20(3):233-6.
DOI: https://doi.org/10.21101/cejph.a3712
Aghsaei Fard Z, Pourshams A, Jafari E, Malekzadeh R. Oral and Dental Health Status in Northeastern Iran, Govaresh, 2009;13(3), 153.
Dar NA, Islami F, Bhat GA, Shah IA, Makhdoomi MA, Iqbal B, Rafiq R, Lone MM, Abnet CC, Boffetta P. Poor oral hygiene and risk of esophageal squamous cell carcinoma in Kashmir. Br J Cancer. 2013 Sep 3;109(5):1367-72. Epub 2013 Jul 30.
DOI: https://doi.org/10.1038/bjc.2013.437
Meurman JH. Oral microbiota and cancer. J Oral Microbiol. 2010 Aug 10;2. doi: 10.3402/jom.v2i0.5195.
DOI: https://doi.org/10.3402/jom.v2i0.5195
Zheng TZ, Boyle P, Hu HF, Duan J, Jian PJ, Ma DQ, Shui LP, Niu SR, Scully C, MacMahon B. Dentition, oral hygiene, and risk of oral cancer: a case-control study in Beijing, People's Republic of China. Cancer Causes Control. 1990 Nov;1(3):235-41. doi: 10.1007/BF00117475.
DOI: https://doi.org/10.1007/BF00117475
Stolzenberg-Solomon RZ, Dodd KW, Blaser MJ, Virtamo J, Taylor PR, Albanes D. Tooth loss, pancreatic cancer, and Helicobacter pylori. Am J Clin Nutr. 2003 Jul;78(1):176-81. PMID: 12816788.
DOI: https://doi.org/10.1093/ajcn/78.1.176
How to Cite
Hosainzadegan, H., Parvan, R., & Hosainzadegan, M. (2022). A retrospective study comparing oral health in cancer patients and healthy people. European Journal of Translational Myology, 32(4). https://doi.org/10.4081/ejtm.2022.10672
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