Platelet-rich plasma therapy or arthroscopic surgery on repair of anterior cruciate ligament rupture

Submitted: 15 April 2022
Accepted: 19 April 2022
Published: 1 August 2022
Abstract Views: 1376
PDF: 900
HTML: 17
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

The Anterior Cruciate Ligament (ACL) rupture reduces knee stability. In old patients with ACL rupture, surgery is not recommended due to the person's low level of activity and knee osteoarthritis. Platelet-rich plasma (PRP) is a good treatment option in inflammatory cases in orthopedics. Hence, the aim of this study was to assess and comparison of the effect of PRP and arthroscopic surgery on anterior cruciate ligament rupture. This is a clinical trial that was performed in 2020-2021 in Tehran. 100 patients were randomly divided into two groups. The first group of patients underwent ACL tendon repair surgery by arthroscopy and tendon graft. The second group were treated by PRP injection. Both groups of patients were visited from 3 months to 14 months after surgery or PRP treatments. The pain was assessed by Visual Analogue Scale (VAS), we also used Knee Score by the Oxford Score Knee Outcome Scale (OKS) to assess patient’s functions. The mean VAS score was 3.05 ± 2.47 in patients in surgery group and mean VAS score was 4.39± 2.66 in patients in the PRP group (p = 0.03). These data showed significant improvements in VAS score in both groups with higher improvements in surgical group. After procedures, the ROM was 120.33 ± 19.60º in surgery group and 109.31 ± 17.22º in PRP group (p = 0.03). Patients in both groups had significantly decreased pain severity after 14 months, but the patients in the surgical treatment group had significantly lower pain and higher ROM compared to PRP group.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Raines BT, Naclerio E, Sherman SL. Management of Anterior Cruciate Ligament Injury: What's In and What's Out? Indian J Orthop. 2017 Sep-Oct;51(5):563-575. PMID: 28966380; PMCID: PMC5609378. DOI: https://doi.org/10.4103/ortho.IJOrtho_245_17
Werner BC, Yang S, Looney AM, Gwathmey FW Jr. Trends in Pediatric and Adolescent Anterior Cruciate Ligament Injury and Reconstruction. J Pediatr Orthop. 2016 Jul-Aug;36(5):447-52. DOI: https://doi.org/10.1097/BPO.0000000000000482
Wetters N, Weber AE, Wuerz TH, Schub DL, Mandelbaum BR. Mechanism of injury and risk factors for anterior cruciate ligament injury. Operative Techniques in Sports Medicine. 2016;24(1):2-6. DOI: https://doi.org/10.1053/j.otsm.2015.09.001
Andalib A, Etemadifar MR, Rafiee Zadeh A, Moshkdar P. Treatment of pilon fractures with low profile plates. Int J Burns Trauma. 2021 Dec 15;11(6):486-493.
Parsons JL, Coen SE, Bekker S. Anterior cruciate ligament injury: towards a gendered environmental approach. Br J Sports Med. 2021 Sep;55(17):984-990. Epub 2021 Mar 10. DOI: https://doi.org/10.1136/bjsports-2020-103173
Rafiee Zadeh A, Askari M, Azadani NN, Ataei A, Ghadimi K, Tavoosi N, Falahatian M. Mechanism and adverse effects of multiple sclerosis drugs: a review article. Part 1. Int J Physiol Pathophysiol Pharmacol. 2019 Aug 15;11(4):95-104.
Rafiee Zadeh A, Ghadimi K, Ataei A, Askari M, Sheikhinia N, Tavoosi N, Falahatian M. Mechanism and adverse effects of multiple sclerosis drugs: a review article. Part 2. Int J Physiol Pathophysiol Pharmacol. 2019 Aug 15;11(4):105-114.
Wahlstedt C, Rasmussen-Barr E. Anterior cruciate ligament injury and ankle dorsiflexion. Knee Surg Sports Traumatol Arthrosc. 2015 Nov;23(11):3202-7. Epub 2014 Jun 13. DOI: https://doi.org/10.1007/s00167-014-3123-1
Cimino F, Volk BS, Setter D. Anterior cruciate ligament injury: diagnosis, management, and prevention. Am Fam Physician. 2010 Oct 15;82(8):917-22.
Hagino T, Ochiai S, Senga S, Yamashita T, Wako M, Ando T, Haro H. Meniscal tears associated with anterior cruciate ligament injury. Arch Orthop Trauma Surg. 2015 Dec;135(12):1701-6. Epub 2015 Aug 19. DOI: https://doi.org/10.1007/s00402-015-2309-4
Rafiee Zadeh A, Ghadimi K, Mohammadi B, Hatamian H, Naghibi SN, Danaeiniya A. Effects of estrogen and progesterone on different immune cells related to multiple sclerosis. Caspian Journal of Neurological Sciences. 2018;4(2):83-90. DOI: https://doi.org/10.29252/cjns.4.13.83
Shen L, Jin ZG, Dong QR, Li LB. Anatomical Risk Factors of Anterior Cruciate Ligament Injury. Chin Med J (Engl). 2018 Dec 20;131(24):2960-2967. DOI: https://doi.org/10.4103/0366-6999.247207
Zadeh AR, Farrokhi M, Etemadifar M, Beni AA. Prevalence of benign tumors among patients with multiple sclerosis. American Journal of Experimental and Clinical Research. 2015;2(4):127-32.
Helito CP, Sobrado MF, Giglio PN, Bonadio MB, Pécora JR, Camanho GL, Demange MK. Combined Reconstruction of the Anterolateral Ligament in Patients With Anterior Cruciate Ligament Injury and Ligamentous Hyperlaxity Leads to Better Clinical Stability and a Lower Failure Rate Than Isolated Anterior Cruciate Ligament Reconstruction. Arthroscopy. 2019 Sep;35(9):2648-2654. Epub 2019 Aug 14. DOI: https://doi.org/10.1016/j.arthro.2019.03.059
Rafiee Zadeh A, Falahatian M, Alsahebfosoul F. Serum levels of histamine and diamine oxidase in multiple sclerosis. Am J Clin Exp Immunol. 2018 Dec 20;7(6):100-105.
Bayer S, Meredith SJ, Wilson KW, de Sa D, Pauyo T, Byrne K, McDonough CM, Musahl V. Knee Morphological Risk Factors for Anterior Cruciate Ligament Injury: A Systematic Review. J Bone Joint Surg Am. 2020 Apr 15;102(8):703-718. Erratum in: J Bone Joint Surg Am. 2020 Jul 15;102(14):e85. DOI: https://doi.org/10.2106/JBJS.19.00535
Wellsandt E, Failla MJ, Snyder-Mackler L. Limb Symmetry Indexes Can Overestimate Knee Function After Anterior Cruciate Ligament Injury. J Orthop Sports Phys Ther. 2017 May;47(5):334-338. Epub 2017 Mar 29. DOI: https://doi.org/10.2519/jospt.2017.7285
Duchman KR, Lynch TS, Spindler KP. Graft Selection in Anterior Cruciate Ligament Surgery: Who gets What and Why? Clin Sports Med. 2017 Jan;36(1):25-33. Epub 2016 Oct 15. DOI: https://doi.org/10.1016/j.csm.2016.08.013
Kaeding CC, Pedroza AD, Reinke EK, Huston LJ, Hewett TE, Flanigan DC; MOON Knee Group, Spindler KP. Change in Anterior Cruciate Ligament Graft Choice and Outcomes Over Time. Arthroscopy. 2017 Nov;33(11):2007-2014. Epub 2017 Aug 26.
Figueroa D, Figueroa F, Calvo R, Vaisman A, Ahumada X, Arellano S. Platelet-rich plasma use in anterior cruciate ligament surgery: systematic review of the literature. Arthroscopy. 2015 May;31(5):981-8. Epub 2015 Jan 14.. DOI: https://doi.org/10.1016/j.arthro.2014.11.022
Hutchinson ID, Rodeo SA, Perrone GS, Murray MM. Can platelet-rich plasma enhance anterior cruciate ligament and meniscal repair? J Knee Surg. 2015 Feb;28(1):19-28. Epub 2014 Aug 7. DOI: https://doi.org/10.1055/s-0034-1387166
Everhart JS, Cavendish PA, Eikenberry A, Magnussen RA, Kaeding CC, Flanigan DC. Platelet-Rich Plasma Reduces Failure Risk for Isolated Meniscal Repairs but Provides No Benefit for Meniscal Repairs With Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2019 Jul;47(8):1789-1796. Epub 2019 Jun 5. DOI: https://doi.org/10.1177/0363546519852616
Davey MS, Hurley ET, Withers D, Moran R, Moran CJ. Anterior Cruciate Ligament Reconstruction with Platelet-Rich Plasma: A Systematic Review of Randomized Control Trials. Arthroscopy. 2020 Apr;36(4):1204-1210. Epub 2020 Jan 25. DOI: https://doi.org/10.1016/j.arthro.2019.11.004
Andriolo L, Di Matteo B, Kon E, Filardo G, Venieri G, Marcacci M. PRP Augmentation for ACL Reconstruction. Biomed Res Int. 2015;2015:371746. Epub 2015 May 5. DOI: https://doi.org/10.1155/2015/371746

How to Cite

Eslami, S., Fattah, S., Taher, S. A., & Rezasoltani, Z. (2022). Platelet-rich plasma therapy or arthroscopic surgery on repair of anterior cruciate ligament rupture. European Journal of Translational Myology, 32(3). https://doi.org/10.4081/ejtm.2022.10538

Similar Articles

You may also start an advanced similarity search for this article.