https://doi.org/10.4081/ejtm.2022.10351
Simultaneous application of transcranial magnetic stimulation and low-frequency electrostatic field as treatment of carbohydrate and lipid disorders in patients with metabolic syndrome
Submitted: 3 January 2022
Accepted: 22 January 2022
Published: 22 February 2022
Accepted: 22 January 2022
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The metabolic syndrome, which covers a wide variety of pathological concerns, is rapidly becoming a global pandemic. This syndrome is difficult to treat pharmacologically. Physiotherapy techniques, which have both local and systemic effects, can be employed as a suitable substitute. The purpose of this study was to investigate the therapeutic effects of a program of simultaneous physiotherapy that included migrant transcranial magnetic stimulation (TMS) and the exposure to an alternating low-frequency electrostatic field (LFEF) in the treatment of metabolic syndrome patients. Ninety patients were randomly assigned to three study groups. While continuing the usual drug therapy the first group (30 patients) received LFEF intervention, the second group (30 patients) received TMS, and the third group (30 patients) underwent the simultaneous use of these non-invasive techniques (LFEF + TMS). All treatments involved 10 sessions with daily frequency. In all the patients before and after treatment body weight, blood pressure parameters, levels of insulin, cortisol, glucose, total cholesterol, high density lipoproteins, malondialdehyde, and Schiff bases, the activity of the antioxidant enzymes catalase and of the superoxide dismutase were studied. The changes in the outcomes assessed revealed a different reaction to therapy with LFEF or TMS, as well as a greater benefit when both treatments were used at the same time. A simultaneous LFEF and TMS intervention seems a promising resource for the treatment of the metabolic syndrome, particularly of the lipid and carbohydrate metabolism disorders. However, further studies are needed to confirm these findings and investigate the underlying mechanisms.
Uspensky Yu P, Fominykh Yu A, Ivanov SV, Niyazov RM. Metabolic syndrome as a problem of topical medicine and the future of mankind. Medicine: theory and practice. 2018;3(1):95-99.
Sokolov DA The risk of developing cardiovascular diseases in people with metabolic syndrome. Bulletin of the Russian Military Medical Academy. 2019;3 (1): 15-17.
Fedash VV. Association of insulin resistance with hypertension and the risk of cardiovascular diseases. Science Time (Moldova). 2020;11(83): S.56-62.
Nilsson PM, Tuomilehto J, Rydén L. The metabolic syndrome - What is it and how should it be managed?. Eur J Prev Cardiol. 2019;26 (2_suppl):33-46.
DOI: https://doi.org/10.1177/2047487319886404
McCracken E, Monaghan M, Sreenivasan S. Pathophysiology of the metabolic syndrome. Clin Dermatol. 2018;36(1):14-20.
DOI: https://doi.org/10.1016/j.clindermatol.2017.09.004
Kulchitskaya DB, Turova EA, Nesterova EV. Application of non-drug methods of treatment in patients with metabolic syndrome. Questions of balneology, physiotherapy and medical physical culture. 2020;97(6-2:63-64.
Khadartsev AA, Logatkina AV, Terekhov IV, Bondar SS. Dynamics of manifestations of metabolic syndrome in patients with arterial hypertension against the background of the combined use of low-intensity microwave therapy. Arterial hypertension. 2018;24(2):206-216.
DOI: https://doi.org/10.18705/1607-419X-2018-24-2-206-216
Ponomarenko GN. Innovative technologies of physiotherapy. Topical issues of physiotherapy: Selected lectures. 2010; pag. 112-135.
Fedotchenko AA, Fedotchenko AA. Electrophysiological and neurohumoral mechanisms of physiotherapy. Acta Biomedica Scientifica. 2017;2(4):115-118.
DOI: https://doi.org/10.12737/article_59fad5126a43f1.27443409
Ulashchik VS. Combined physiotherapy: general information, interaction of physical factors. Problems of balneology, physiotherapy and medical physical culture. 2016;6:4-11.
DOI: https://doi.org/10.17116/kurort201664-11
Orekhova EM, Konchugova TV, Kul'chitskaya DB, Korchazhkina NB, Egorova LA, Chuich NG. Modern approaches to the use of neurotropic physical therapy in arterial hypertension. Vopr Kurortol Fizioter Lech Fiz Kult. 2016 May-Jun;93(3):53-55. Russian.
DOI: https://doi.org/10.17116/kurort2016353-55
Xiao LJ, Tao R. Physical Therapy. Adv Exp Med Biol. 2017;1010:247-260.
DOI: https://doi.org/10.1007/978-981-10-5562-1_12
Yakovlev M Yu, Tumanova-Ponomareva NF, Fesyun AD, Ismailova LA, Ambrazhuk II The effectiveness of the school of health in a sanatorium for patients with acute coronary syndrome. Russian Journal of Rehabilitation Medicine. 2020;3:78-89.
Saltykova MM, Shopina OV, Balakaeva AV, Bobrovnitskiy IP Air pollution as a factor in the increased mortality of the population. Russian Journal of Rehabilitation Medicine. 2020;4:4-16.
Bobrovnitskiy IP, Nagornev SN, Khudov VV, Yakovlev My. The main directions of improving the activities of health centers in the Arctic zone of the Russian Federation. Russian Journal of Rehabilitation Medicine. 2020;3:35-55.
Göbel CH, Tronnier VM, Münte TF. Brain stimulation in obesity. Int J Obes (Lond). 2017;41(12):1721-1727.
DOI: https://doi.org/10.1038/ijo.2017.150
Kulish AV. A systematic approach to the use of transcranial magnetic effects in the rehabilitation of patients with chronic non-infectious diseases. 2017; p. 48
Kulikov AG, Yarustovskaya OV, Kuzovleva EV. Application of low-frequency electrostatic field in clinical practice. Russian Journal of Physiotherapy, Balneology and Rehabilitation. 2019;18(3):195-209.
DOI: https://doi.org/10.17816/1681-3456-2019-18-3-195-209
Gavrilov VB, Gavrilova AR, Mazhul LM. Analysis of methods for the determination of LPO products in serum by the test with TBC. Questions of medical chemistry. 1987;1:118-122.
Korolyuk MA, Ivanova LI, Mayorova IG, Tokarev VE. Method for determining the activity of catalase. Clinical laboratory diagnostics. 1988;1:16-19.
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985 Jul;28(7):412-9.
DOI: https://doi.org/10.1007/BF00280883
Klimov AN, Parfenova NS, Golikov IuP One century of the cholesterol model of atherosclerosis /Biomed Khim 2012;58(1):5-11.
DOI: https://doi.org/10.18097/pbmc20125801005
Mikhailenko LV, Nagornev SN, Bobrovnitsky IP, Frolkov VK. Phytotherapy of arterial hypertension in combination with obesity in sanatorium-resort conditions. Questions of balneology, physiotherapy and medical physical culture. 2009;5:13-17.
Mikhailenko LV, Bobrovnitsky IP, Nagornev SN, Frolkov VK. Predictor significance of the initial morphological and functional indicators in assessing the effectiveness of the rehabilitation correction of arterial hypertension. Questions of balneology, physiotherapy and medical physical culture. 2010;2:35-38.
Frolkov V K, Edelev D A Mineral waters effects on metabolic syndrome (a clinico-experimental trial) Vopr Kurortol Fizioter Lech Fiz Kult. -2006;(3):26-8.
Masiero S, Vittadini F, Ferroni C, Bosco A, Serra R, Frigo AC, Frizziero A. The role of thermal balneotherapy in the treatment of obese patient with knee osteoarthritis. Int J Biometeorol. 2018 Feb;62(2):243-252. Epub 2017 Sep 22.
DOI: https://doi.org/10.1007/s00484-017-1445-7
Masiero S, Maccarone MC, Agostini F. Health resort medicine can be a suitable setting to recover disabilities in patients tested negative for COVID-19 discharged from hospital? A challenge for the future. Int J Biometeorol. 2020;64(10):1807-1809.
DOI: https://doi.org/10.1007/s00484-020-01947-4
Filaretov AA, Vassilevskaya LV. Electrical activity of hypothalamus during activation of pituitary-adrenocortical system Brain Res. 1978 Nov 3;156(1):67-74.
DOI: https://doi.org/10.1016/0006-8993(78)90079-3
Wei W, Li X, Hao J, Zhang R, Guo J, Zong Y, Lu Y, Qu S, Tian J. Proteomic analysis of functional dyspepsia in stressed rats treated with traditional Chinese medicine "Wei Kangning". J Gastroenterol Hepatol. 2011 Sep;26(9):1425-33.
DOI: https://doi.org/10.1111/j.1440-1746.2011.06566.x
Jafari MJ, Khosrowabadi R, Khodakarim S, Khodagholi F, Mohammadian F. The effects of combined exposure to noise and heat on human salivary cortisol and blood pressure. Int J Occup Saf Ergon. 2021 Sep;27(3):831-839. Epub 2019 Oct 4.
DOI: https://doi.org/10.1080/10803548.2019.1659578
How to Cite
Andrey A. Benkov, Nagornev, S. N., Frolkov, V. K., Reps, V. F., Edelev, D. A., Fesyun, A. D., Yakovlev, M. Y., Tumanova, N. F., Sanina, N. P., Maccarone, M. C., & Stefano Masiero. (2022). Simultaneous application of transcranial magnetic stimulation and low-frequency electrostatic field as treatment of carbohydrate and lipid disorders in patients with metabolic syndrome. European Journal of Translational Myology, 32(1). https://doi.org/10.4081/ejtm.2022.10351
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