https://doi.org/10.4081/aiua.2024.12228

Endoscopic enucleation of the prostate with Thulium Fiber Laser (ThuFLEP). A retrospective single-center study

Vol. 96 No. 1 (2024)
Submitted: December 23, 2023
Accepted: January 3, 2024
Published: February 16, 2024
Benign prostatic hyperplasia, enucleation, prostate, ThuFLEP, thulium
Abstract Views: 402
PDF: 270
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Authors

Angelis Peteinaris
https://orcid.org/0000-0002-0427-4506
Department of Urology, University of Patras, Greece.
Vasileios Tatanis
tatanisbas@gmail.com
https://orcid.org/0000-0002-8584-3888
Department of Urology, University of Patras, Greece.
Paraskevi Katsakiori
https://orcid.org/0009-0001-1640-1058
Department of Urology, University of Patras, Greece.
Theodoros Spinos
Department of Urology, University of Patras, Greece.
Solon Faitatziadis
Department of Urology, University of Patras, Greece.
Kristiana Gkeka
https://orcid.org/0000-0003-3876-8931
Department of Urology, University of Patras, Greece.
Anastasios Natsos
https://orcid.org/0000-0002-5845-7420
Department of Urology, University of Patras, Greece.
Theofanis Vrettos
Department of Anesthesiology and ICU, University of Patras, Greece.
Evangelos Liatsikos
https://orcid.org/0000-0002-8584-3888
Department of Urology, University of Patras, Greece.
Panagiotis Kallidonis
Department of Urology, University of Patras, Greece.

Purpose: The aim of the present, retrospective study was to describe our initial experience and early outcomes of Thulium Fiber Laser enucleation of the prostate (ThuFLEP) with the use of the FiberDust™ (Quanta System, Samarate, Italy) in patients with benign prostate hyperplasia.
Methods: From June 2022 to April 2023, all patients who underwent endoscopic enucleation of the prostate at Urology Department of the University Hospital of Patras were included. A single surgeon utilizing the same standardized operative technique performed all the surgeries. The primary endpoints included the uneventful completion of the operation, the surgical time and any minor or major complication observed intra- or post-operatively.
Results: Twenty patients with benign prostate hyperplasia were treated with ThuFLEP. All the surgeries were completed successfully and uneventfully. The enucleation phase of the operation was completed in a mean time of 45±9.1 min, while the average time needed for the morcellation was 17.65±3.42 min. No significant complications were observed intra- or post-operatively. The average hemoglobin drop was calculated to be 0.94±0.71 g/dL.
Conclusions: All the operations were successfully and efficiently completed with the use of the FiberDust™ (Quanta System, Samarate, Italy) in ThuFLEP. Significant blood loss or major complications were not observed.

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Scopus
Google Scholar
Europe PMC
Lee SWH, Chan EMC, Lai YK. The global burden of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: A systematic review and meta-analysis. Sci Rep 2017; 7:7984. DOI: https://doi.org/10.1038/s41598-017-06628-8
Cornu JN, Ahyai S, Bachmann A, et al. A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update. Eur Urol 2015; 67:1066-96. DOI: https://doi.org/10.1016/j.eururo.2014.06.017
Elzayat EA, Elhilali MM. Holmium laser enucleation of the prostate (HoLEP): long-term results, reoperation rate, and possible impact of the learning curve. Eur Urol 2007; 52:1465-71. DOI: https://doi.org/10.1016/j.eururo.2007.04.074
Brunckhorst O, Ahmed K, Nehikhare O, et al. Evaluation of the Learning Curve for Holmium Laser Enucleation of the Prostate Using Multiple Outcome Measures. Urology 2015; 86:824-9. DOI: https://doi.org/10.1016/j.urology.2015.07.021
Nair SM, Pimentel MA, Gilling PJ. A Review of Laser Treatment for Symptomatic BPH (Benign Prostatic Hyperplasia). Curr Urol Rep 2016; 17:45. DOI: https://doi.org/10.1007/s11934-016-0603-5
Denstedt J, Gabrigna Berto FC. Thulium fiber laser lithotripsy: Is it living up to the hype? Asian J Urol 2023; 10:289-97. DOI: https://doi.org/10.1016/j.ajur.2022.11.003
Doizi S, Germain T, Panthier F, et al. Comparison of Holmium:YAG and Thulium Fiber Lasers on Soft Tissue: An Ex Vivo Study. J Endourol 2022; 36:251-8. DOI: https://doi.org/10.1089/end.2021.0263
Saitta G, Becerra JEA, Del Álamo JF, et al. 'En Bloc' HoLEP with early apical release in men with benign prostatic hyperplasia. World J Urol 2019; 37:2451-8. DOI: https://doi.org/10.1007/s00345-019-02671-4
Pan TT, Li SQ, Dai Y, Qi JX. Observation of complications assessed by Clavien-Dindo classification in different endoscopic procedures of benign prostatic hyperplasia: An observational study. Medicine 2023; 102:e32691. DOI: https://doi.org/10.1097/MD.0000000000032691
Katta N, Santos D, McElroy AB, et al. Laser coagulation and hemostasis of large diameter blood vessels: effect of shear stress and flow velocity. Sci Rep 2022; 12:8375. DOI: https://doi.org/10.1038/s41598-022-12128-1
Fraundorfer MR, Gilling PJ. Holmium:YAG laser enucleation of the prostate combined with mechanical morcellation: preliminary results. Eur Urol 1998; 33:69-72. DOI: https://doi.org/10.1159/000019535
Hiraoka Y. A new method of prostatectomy, transurethral detachment and resection of benign prostatic hyperplasia. Nihon Ika Daigaku zasshi. 1983; 50:896-8. DOI: https://doi.org/10.1272/jnms1923.50.896
Oh SJ. Current surgical techniques of enucleation in holmium laser enucleation of the prostate. Invest Clinl Urol 2019; 60:333-42. DOI: https://doi.org/10.4111/icu.2019.60.5.333
Scoffone CM, Cracco CM. The en-bloc no-touch holmium laser enucleation of the prostate (HoLEP) technique. World J Urol 2016; 34:1175-81. DOI: https://doi.org/10.1007/s00345-015-1741-y
Schembri M, Sahu J, Aboumarzouk O, et al. Thulium fiber laser: The new kid on the block. Turk J Urol 2020; 46:S1-s10. DOI: https://doi.org/10.5152/tud.2020.20093
Hartung FO, Kowalewski KF, von Hardenberg J, et al. Holmium Versus Thulium Laser Enucleation of the Prostate: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Eur Urol Focus 2022; 8:545-54. DOI: https://doi.org/10.1016/j.euf.2021.03.024
Enikeev D, Netsch C, Rapoport L, et al. Novel thulium fiber laser for endoscopic enucleation of the prostate: A prospective comparison with conventional transurethral resection of the prostate. IJU 2019; 26:1138-43. DOI: https://doi.org/10.1111/iju.14115
Pirola GM, Saredi G, Codas Duarte R, et al. Holmium laser versus thulium laser enucleation of the prostate: a matched-pair analysis from two centers. Ther Adv Urol 2018; 10:223-33. DOI: https://doi.org/10.1177/1756287218779784
Chang C-H, Lin T-P, Huang J-Y. Safety and effectiveness of highpower thulium laser enucleation of the prostate in patients with glands larger than 80 mL. BMC Urol 2019; 19:8. DOI: https://doi.org/10.1186/s12894-019-0437-9
Enikeev D, Okhunov Z, Rapoport L, et al. Novel Thulium Fiber Laser for Enucleation of Prostate: A Retrospective Comparison with Open Simple Prostatectomy. J Endourol 2019; 33:16-21. DOI: https://doi.org/10.1089/end.2018.0791
Evangelos Liatsikos, Department of Urology, University of Patras

Department of Urology, Medical University of Vienna, Austria

How to Cite

Peteinaris, A., Tatanis, V., Katsakiori, P., Spinos, T., Faitatziadis, S., Gkeka, K., Natsos, A., Vrettos, T., Liatsikos, E., & Kallidonis, P. (2024). Endoscopic enucleation of the prostate with Thulium Fiber Laser (ThuFLEP). A retrospective single-center study. Archivio Italiano Di Urologia E Andrologia, 96(1). https://doi.org/10.4081/aiua.2024.12228
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