Molecular evaluation of 7 sexually transmissible microorganisms in symptomatic and asymptomatic Italian childbearing age women: is Ureaplasma parvum a real innocent bystander?
Submitted: 4 March 2016
Accepted: 7 May 2016
Published: 18 October 2016
Accepted: 7 May 2016
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Materials and Methods: DNA of 2735 endocervical specimens was consecutively analysed by a commercial multiplex real-time polymerase chain reaction for detection of 7 multiple target sequences simultaneously: CT, NG, TV, MG, MH, UU and UP.
Results: Out of the total number of population studied (n=2735), UP was found to be the species with highest prevalence (30.9%) followed by MH (6.5%), UU (6.3%), CT (2.6%), MG (0.8%) and TV (0.9%). UP single species detection was extremely significant in symptomatic women with normal flora (P<0.0001). The correlation of UP in symptomatic women with bacterial vaginosis was not significant (P=0.3387).
Conclusions: Our results suggest a potential specific etiological role to UP, still considered rightly or wrongly innocent bystander, despite the lack so far of specific-species culture tests.
Avolio, M., Modolo, M. L., Stano, P., De Rosa, R., & Camporese, A. (2016). Molecular evaluation of 7 sexually transmissible microorganisms in symptomatic and asymptomatic Italian childbearing age women: is Ureaplasma parvum a real innocent bystander?. Microbiologia Medica, 31(3). https://doi.org/10.4081/mm.2016.5864
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