Current antimicrobial sensitivity pattern of typhoidal salmonellae in a referral diagnostic centre
Submitted: 15 August 2014
Accepted: 25 November 2015
Published: 31 March 2016
Accepted: 25 November 2015
Abstract Views: 1658
PDF: 774
HTML: 503
HTML: 503
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Aim: To ascertain the current susceptibility pattern of typhoidal salmonellae thus guiding the physicians for better management of typhoid patients.
Materials and Methods: A study was conducted at our institution from January 2012 through December 2013 to investigate current susceptibility pattern of typhoidal salmonellae.
Results: Out of 200 isolates, 107 (53.5%) were identified as Salmonella Typhi and 93 (46.5%) as Salmonella Paratyphi A. Sensitivities of Salmonella Typhi were as follows: ampicillin (48.6%), chloramphenicol (45.8%), co-trimoxazole (40.1%), ciprofloxacin (11.2%). Sensitivities of Salmonella Paratyphi A were: ampicillin (80.6%), chloramphenicol (89.2%), co-trimoxazole (90.3%), and ciprofloxacin (16.1%). No resistance was detected against third generation cephalosporins.
Conclusions: Typhoidal salmonellae are still entirely susceptible to third generation cephalosporins in our setting. Marked rise in resistance to fluoroquinolones has reduced their empirical usage. Sensitivity of Salmonella Paratyphi A to conventional antityphoid drugs was encouraging.
Supporting Agencies
Armed Forces Institute of Pathology, PakistanShujat, U., Ikram, A., Hashmi, I. Q. J., Abbasi, S. A., Afzal, A., & Ayyub, M. (2016). Current antimicrobial sensitivity pattern of typhoidal salmonellae in a referral diagnostic centre. Microbiologia Medica, 31(1). https://doi.org/10.4081/mm.2016.4669
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.