Valutazione dell’antibiotico-resistenza nell’acne

Acne is a multifactorial disease whose clinical features include infiammatory and non-infiammatory lesions. The aim of this study is to define possible guidelines for the treatment of this disease, taking into account the problems caused by antibiotic resistance and the side effect of antibiotics. From april 2000 to december 2002, 841 skin swab have been performed to detect the Propionbacteria, the agents more commonly related to the occurrence of acne. The results showed a correlation between low therapeutic response and antibiotic resistance, mainly concerning erytromycin (412/841-52.2%). Further investigations should be carried out in the near future, to clarify and understand the clinical effects of the resistant strain, and to overcome the lack of efficacy of the current antibiotic therapies.