Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis


https://doi.org/10.4081/mm.2010.2479
Vol. 25 No. 1 (2010)
Submitted: 14 February 2014
Accepted: 14 February 2014
Published: 31 March 2010
Antimicrobial associations, Antimicrobial susceptibility, Enterococcus, Infective endocarditis
Abstract Views: 1392
PDF: 1545
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The epidemiological and clinical study “Studio Endocarditi Italiane” (SEI) evaluated 947 cases of infective endocarditis in 2004-2008. Enterococcal aethiology was described in 11% cases.The aim of our study was to evacuate the in vitro activity of twelve antibiotics alone and in association against 20 strains (15 E. faecalis, 5 E. faecium). Results show the in vitro activity of tigecyicline, daptomicine and linezolid. Synergism is appreciated for ceftriaxone-fosfomycin (FICindex50=0.34, FICindex90=0.56) against E. faecalis and for imipenem-fosfomycin against E. faecium.The majority of the tested strains show addition using ampicillin-ceftriaxone (FICindex50=0.85, FICindex90=1.01) and moxifloxacin- tigecycline (FICindex50=0.77, FICindex90=1.96).

Farina, C., Russello, G., Raglio, A., Vailati, F., Ravasio, V., Pasticci, M. B., Chinello, P., Scarparo, C., & SEI, G. (2010). Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis. Microbiologia Medica, 25(1). https://doi.org/10.4081/mm.2010.2479

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