https://doi.org/10.4081/mm.2010.2479

Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis

Vol. 25 No. 1 (2010)
Submitted: 14 February 2014
Accepted: 14 February 2014
Published: 31 March 2010
Antimicrobial associations, Antimicrobial susceptibility, Enterococcus, Infective endocarditis
Abstract Views: 1417
PDF: 1568
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Authors

Claudio Farina
farina.claudio@sancarlo.mi.it
Giuseppe Russello
Annibale Raglio
Francesca Vailati
Veronica Ravasio
Maria Bruna Pasticci
Pierangelo Chinello
Claudio Scarparo
Gruppo SEI
The epidemiological and clinical study “Studio Endocarditi Italiane” (SEI) evaluated 947 cases of infective endocarditis in 2004-2008. Enterococcal aethiology was described in 11% cases.The aim of our study was to evacuate the in vitro activity of twelve antibiotics alone and in association against 20 strains (15 E. faecalis, 5 E. faecium). Results show the in vitro activity of tigecyicline, daptomicine and linezolid. Synergism is appreciated for ceftriaxone-fosfomycin (FICindex50=0.34, FICindex90=0.56) against E. faecalis and for imipenem-fosfomycin against E. faecium.The majority of the tested strains show addition using ampicillin-ceftriaxone (FICindex50=0.85, FICindex90=1.01) and moxifloxacin- tigecycline (FICindex50=0.77, FICindex90=1.96).

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How to Cite

Farina, C., Russello, G., Raglio, A., Vailati, F., Ravasio, V., Pasticci, M. B., Chinello, P., Scarparo, C., & SEI, G. (2010). Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis. Microbiologia Medica, 25(1). https://doi.org/10.4081/mm.2010.2479

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