Diabetes mellitus and upper gut motility

Submitted: April 10, 2014
Accepted: April 10, 2014
Published: January 30, 2013
Abstract Views: 944
PDF: 940
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The aim of the study is to detect the presence of esophageal motor disorders in type I and II diabetic patients, and to establish whether there is any difference between patients with and without neuropathy. 118 diabetics patients (34 type I and 84 type II) were investigated by water-perfused stationary esophageal manometry. Data were correlated with the presence of peripheral neurophaty. As a result 71% of patients affected by peripheral neuropathy showed manometric abnormalities against the 37% of the patients without neuropathy. Our experience has shown that patients with diabetes mellitus frequently present esophageal symptoms and manometric abnormalities. Manometric study of the esophagus has to be considered a useful investigative tool to manage and monitorize the gastrointestinal abnormalities in patients affected by diabetes mellitus.

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Mandolfino, F., Frascio, M., Perotti, S., Lazzara, F., Imperatore, M., & Bruno, S. (2013). Diabetes mellitus and upper gut motility. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 86(1). https://doi.org/10.4081/jbr.2013.3670