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Electrical stimulation counteracts muscle atrophy associated with aging in humans

Helmut Kern, Stefan Loefler, Samantha Burggraf, Hannah Fruhmann, Jan Cvecka, Milan Sedliak, Laura Barberi, Manuela De Rossi, Antonio Musarò, Ugo Carraro, Simone Mosole, Sandra Zampieri
  • Stefan Loefler
    Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria,
  • Samantha Burggraf
    Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria,
  • Hannah Fruhmann
    Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria,
  • Jan Cvecka
    Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia,
  • Milan Sedliak
    Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia,
  • Laura Barberi
    DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy,
  • Manuela De Rossi
    DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy,
  • Antonio Musarò
    DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy,
  • Ugo Carraro
    Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy,
  • Simone Mosole
    Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy,
  • Sandra Zampieri
    Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy,

Abstract

Functional and structural muscle decline is a major problem during aging. Our goal was to improve in old subjects quadriceps m. force and mobility functional performances (stair test, chair rise test, timed up and go test) with neuromuscular electrical stimulation (9 weeks, 2-3times/week, 20-30 minutes per session). Furthermore we performed histological and biological molecular analyses of vastus lateralis m. biopsies. Our findings demonstrate that electrical stimulation significantly improved mobility functional performancies and muscle histological characteristics and molecular markers.

Keywords

electrical stimulation, FES, NMES, senior, muscle decline, aging, atrophy

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Submitted: 2013-06-25 18:40:52
Published: 2013-07-25 00:00:00
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Copyright (c) 2013 Helmut Kern, Stefan Loefler, Samantha Burggraf, Hannah Fruhmann, Jan Cvecka, Milan Sedliak, Laura Barberi, Manuela De Rossi, Antonio Musarò, Ugo Carraro, Simone Mosole, Sandra Zampieri

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