https://doi.org/10.4081/ejtm.2014.3790

Neurohypophyseal hormones: novel actors of striated muscle development and homeostasis

Vol. 24 No. 3 (2014)
Submitted: 15 April 2014
Accepted: 15 September 2014
Published: 22 September 2014
Arginine-vasopressin, oxytocin, skeletal myogenic cells and cardiomyocite differentiation and homeostasis, receptors and signal transduction mechanisms
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Authors

Alessandra Costa
Histology and Medical Embryology Section, Dept. AHFMO, Sapienza University, Rome; I.I.M., Interuniversity Institute of Myology, Italy.
Eleonora Rossi
Histology and Medical Embryology Section, Dept. AHFMO, Sapienza University, Rome, Italy.
Bianca Maria Scicchitano
Histology and Medical Embryology Section, Dept. AHFMO, Sapienza University, Rome; I.I.M., Interuniversity Institute of Myology; Institute of Histology and Embryology, Catholic University School of Medicine, Rome, Italy.
Dario Coletti
Histology and Medical Embryology Section, Dept. AHFMO, Sapienza University, Rome; I.I.M., Interuniversity Institute of Myology, Italy.
Viviana Moresi
Histology and Medical Embryology Section, Dept. AHFMO, Sapienza University, Rome, Italy.
Sergio Adamo
sergio.adamo@uniroma1.it
Histology and Medical Embryology Section, Dept. AHFMO, Sapienza University, Rome; I.I.M., Interuniversity Institute of Myology, Italy.
Since the 1980's, novel functional roles of the neurohypophyseal hormones vasopressin and oxytocin have emerged. Several studies have investigated the effects of these two neurohormones on striated muscle tissues, both in vitro and in vivo. The effects of vasopressin on skeletal myogenic cells, developing muscle and muscle homeostasis have been documented. Oxytocin appears to have a greater influence on cardiomyocite differentiation and heart homeostasis. This review summarizes the studies on these novel roles of the two neurohypophyseal hormones, and open the possibility of new therapeutic approaches for diseases affecting striated muscle.

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Supporting Agencies

Italian Ministry of Education (MIUR), Sapienza University of Rome, French Muscular Dystrophy Association (AFM), Agence Nationale de la Recherche (ANR), National Institutes of Health (NIH), UPMC Sorbonne Universités,

How to Cite

Costa, A., Rossi, E., Scicchitano, B. M., Coletti, D., Moresi, V., & Adamo, S. (2014). Neurohypophyseal hormones: novel actors of striated muscle development and homeostasis. European Journal of Translational Myology, 24(3). https://doi.org/10.4081/ejtm.2014.3790

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