https://doi.org/10.4081/ejtm.2013.1780
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Electrical stimulation counteracts muscle atrophy associated with aging in humans

Authors

Helmut Kern
wil.pys.kern-forschung@wienkav.at
Department of Physical Medicine and Rehabilitation, Wilhelminenspital, Vienna, .
Stefan Loefler
Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria, .
Samantha Burggraf
Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria, .
Hannah Fruhmann
Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria, .
Jan Cvecka
Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia, .
Milan Sedliak
Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia, .
Laura Barberi
DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy, .
Manuela De Rossi
DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy, .
Antonio Musarò
DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy, .
Ugo Carraro
Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy, .
Simone Mosole
Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy, .
Sandra Zampieri
Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy, .
Functional and structural muscle decline is a major problem during aging. Our goal was to improve in old subjects quadriceps m. force and mobility functional performances (stair test, chair rise test, timed up and go test) with neuromuscular electrical stimulation (9 weeks, 2-3times/week, 20-30 minutes per session). Furthermore we performed histological and biological molecular analyses of vastus lateralis m. biopsies. Our findings demonstrate that electrical stimulation significantly improved mobility functional performancies and muscle histological characteristics and molecular markers.

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Simone Mosole, Ugo Carraro, Helmut Kern, Stefan Loefler, Hannah Fruhmann, Michael Vogelauer, Samantha Burggraf, Winfried Mayr, Matthias Krenn, Tatjana Paternostro-Sluga, Dusan Hamar, Jan Cvecka, Milan Sedliak, Veronika Tirpakova, Nejc Sarabon, Antonio Musarò, Marco Sandri, Feliciano Protasi, Alessandra Nori, Amber Pond, Sandra Zampieri (2014)
Long-Term High-Level Exercise Promotes Muscle Reinnervation With Age. Journal of Neuropathology & Experimental Neurology, 73(4), 284.
10.1097/NEN.0000000000000032
Simone Mosole, Katia Rossini, Helmut Kern, Stefan Löfler, Hannah Fruhmann, Michael Vogelauer, Samantha Burggraf, Martina Grim-Stieger, Ján Cvečka, Dušan Hamar, Milan Sedliak, Nejc Šarabon, Amber Pond, Donatella Biral, Ugo Carraro, Sandra Zampieri (2022)
Reinnervation of Vastus lateralis is increased significantly in seniors (70-years old) with a lifelong history of high-level exercise (2013, revisited here in 2022). European Journal of Translational Myology, 32(1),
10.4081/ejtm.2022.10420

How to Cite

Kern, H., Loefler, S., Burggraf, S., Fruhmann, H., Cvecka, J., Sedliak, M., Barberi, L., De Rossi, M., Musarò, A., Carraro, U., Mosole, S., & Zampieri, S. (2013). Electrical stimulation counteracts muscle atrophy associated with aging in humans. European Journal of Translational Myology, 23(3), 105–108. https://doi.org/10.4081/ejtm.2013.1780

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