Electrical stimulation counteracts muscle atrophy associated with aging in humans

Helmut Kern; Stefan Loefler; Samantha Burggraf; Hannah Fruhmann; Jan Cvecka; Milan Sedliak; Laura Barberi; Manuela De Rossi; Antonio Musarò; Ugo Carraro; Simone Mosole; Sandra Zampieri

doi:10.4081/ejtm.2013.1780

Original Articles Open access

Electrical stimulation counteracts muscle atrophy associated with aging in humans

Authors

Helmut Kern – articles in this journal Corresponding author Email Department of Physical Medicine and Rehabilitation, Wilhelminenspital, Vienna
Stefan Loefler – articles in this journal Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria
Samantha Burggraf – articles in this journal Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria
Hannah Fruhmann – articles in this journal Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria
Jan Cvecka – articles in this journal Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia
Milan Sedliak – articles in this journal Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia
Laura Barberi – articles in this journal DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy
Manuela De Rossi – articles in this journal DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy
Antonio Musarò – articles in this journal DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy
Ugo Carraro – articles in this journal Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy
Simone Mosole – articles in this journal Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy
Sandra Zampieri – articles in this journal Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy

Published: 25 July 2013
Issue: Vol. 23 No. 3 (2013)
Section: Original Articles
DOI: 10.4081/ejtm.2013.1780
Pages: 105-108

Abstract

Functional and structural muscle decline is a major problem during aging. Our goal was to improve in old subjects quadriceps m. force and mobility functional performances (stair test, chair rise test, timed up and go test) with neuromuscular electrical stimulation (9 weeks, 2-3times/week, 20-30 minutes per session). Furthermore we performed histological and biological molecular analyses of vastus lateralis m. biopsies. Our findings demonstrate that electrical stimulation significantly improved mobility functional performancies and muscle histological characteristics and molecular markers.

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Article history

Received: 25 June 2013
Accepted: 25 June 2013
Published: 25 July 2013

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1.

Kern H, Loefler S, Burggraf S, Fruhmann H, Cvecka J, Sedliak M, et al. Electrical stimulation counteracts muscle atrophy associated with aging in humans. Eur J Transl Myol [Internet]. 2013 Jul. 25 [cited 2026 Nov. 6];23(3):105-8. Available from: https://www.pagepressjournals.org/bam/article/view/bam.2013.3.105

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