Original Articles
Vol. 23 No. 3 (2013)
https://doi.org/10.4081/ejtm.2013.1780

Electrical stimulation counteracts muscle atrophy associated with aging in humans

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Received: 25 June 2013
Published: 25 July 2013
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electrical stimulation, FES, NMES, senior, muscle decline, aging, atrophy

Authors

Helmut Kern
wil.pys.kern-forschung@wienkav.at
Department of Physical Medicine and Rehabilitation, Wilhelminenspital, Vienna, .
Stefan Loefler
Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria, .
Samantha Burggraf
Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria, .
Hannah Fruhmann
Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria, .
Jan Cvecka
Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia, .
Milan Sedliak
Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia, .
Laura Barberi
DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy, .
Manuela De Rossi
DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy, .
Antonio Musarò
DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy, .
Ugo Carraro
Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy, .
Simone Mosole
Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy, .
Sandra Zampieri
Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy, .
Functional and structural muscle decline is a major problem during aging. Our goal was to improve in old subjects quadriceps m. force and mobility functional performances (stair test, chair rise test, timed up and go test) with neuromuscular electrical stimulation (9 weeks, 2-3times/week, 20-30 minutes per session). Furthermore we performed histological and biological molecular analyses of vastus lateralis m. biopsies. Our findings demonstrate that electrical stimulation significantly improved mobility functional performancies and muscle histological characteristics and molecular markers.

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1.
Kern H, Loefler S, Burggraf S, Fruhmann H, Cvecka J, Sedliak M, et al. Electrical stimulation counteracts muscle atrophy associated with aging in humans. Eur J Transl Myol [Internet]. 2013 Jul. 25 [cited 2026 Apr. 30];23(3):105-8. Available from: https://www.pagepressjournals.org/bam/article/view/bam.2013.3.105

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