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Diagnosis and treatment in primary bladder small cell carcinoma: Literature review

Orcun Celik, Gokhan Ekin, Tumay Ipekci, Salih Budak, Yusuf Ozlem Ilbey
  • Gokhan Ekin
    Tepecik Educational and Research Hospital, Urology Department, Izmir, Turkey
  • Tumay Ipekci
    Baskent University, Faculty of Medicine, Alanya Research Hospital, Antalya, Turkey
  • Salih Budak
    Tepecik Educational and Research Hospital, Urology Department, Izmir, Turkey
  • Yusuf Ozlem Ilbey
    Tepecik Educational and Research Hospital, Urology Department, Izmir, Turkey

Abstract

Small cell bladder carcinoma is a rare and frequently fatal disease. It can be distinguished from classical urothelial carcinoma microscopically and immunohistochemically. Small cell bladder carcinoma has histologically similar properties with other small cell carcinomas in other organs. It has a worse prognosis when compared to urothelial bladder cancer. Multimodal treatments are recommended although there is no widely accepted consensus regarding to the treatment algorithm because of its rarity. In this review, clinical properties and diagnosis of small cell bladder carcinoma, its histopathological and immunohistochemical properties and treatment modalities are examined.

Keywords

Neuroendocrine carcinoma; Bladder cancer; Small cell cancer

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Submitted: 2016-04-06 16:25:29
Published: 2016-03-31 00:00:00
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Copyright (c) 2016 Orcun Celik, Gokhan Ekin, Tumay Ipekci, Salih Budak, Yusuf Ozlem Ilbey

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