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Prolonged antibiotic therapy increases risk of infection after transrectal prostate biopsy: A case report after pancreasectomy and review of the literature

Guevar Maselli, Giacomo Tucci, Daniele Mazzaferro, Asim Ettamimi, Giulia Sbrollini, Marco Cordari, Gaetano Donatelli, Andrea Benedetto Galosi
  • Guevar Maselli
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy | guevarmaselli@katamail.com
  • Giacomo Tucci
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy
  • Daniele Mazzaferro
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy
  • Asim Ettamimi
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy
  • Giulia Sbrollini
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy
  • Marco Cordari
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy
  • Gaetano Donatelli
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy
  • Andrea Benedetto Galosi
    Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy

Abstract

Infection due to prostate biopsy afflicted more than 5% of patients and is the most common reason for hospitalization. A large series from US SEER-Medicare reported that men undergoing biopsy were 2.26 times more likely to be hospitalized for infectious complications within 30 days compared with randomly selected controls. The factors predicting a higher susceptibility to infection remain largely unknown but some authors have higlighted in the etiopathogenesis the importance of the augmented prevalence of ciprofloxacin resistant variant of bacteria in the rectum flora. We present one case of sepsis after transrectal prostate biopsy in a patient with history of pancreatic surgery. Based on our experience patients candidated to prostate biopsy with transrectal technique with history of recent major surgery represent an high risk category for infective complication. Also major pancreatic surgery should be consider an high risk category for infection. A transperineal approach and preventive measures (such as rectal swab) should be adopted to reduce biopsy driven infection.

Keywords

Prostate; Biopsy; Infection; Sepsis; Abdominal surgery

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Submitted: 2015-01-23 16:18:52
Published: 2014-12-30 00:00:00
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Copyright (c) 2014 Guevar Maselli, Giacomo Tucci, Daniele Mazzaferro, Asim Ettamimi, Giulia Sbrollini, Marco Cordari, Gaetano Donatelli, Andrea Benedetto Galosi

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