https://doi.org/10.4081/aiua.2015.2.147
Evaluation of Tl-201 SPECT imaging findings in prostate cancer
Submitted: July 6, 2015
Accepted: July 6, 2015
Published: July 7, 2015
Accepted: July 6, 2015
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SUPPLEMENTARY MATERIAL: 560
SUPPLEMENTARY MATERIAL: 560
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Methods: The study comprised 59 patients (age range 51-79 years, mean age 65.3 ± 6.8 years) who were planned to have transrectal ultrasonography (TRUS)-guided biopsies due to suspicion of prostate cancer between April 2011 and September 2011. Early planar, late planar and SPECT images were obtained for all patients. Scintigraphic evaluation was made in relation to uptake presence and patterns in the visual assessment and to Tumor/Background (T/Bg) ratios for both planar and SPECT images in the quantitative assessment. Histopathological findings were compatible with benign etiology in 36 (61%) patients and malign etiology in 23 (39%) patients. Additionally, comparisons were made to evaluate the relationships between uptake patterns,total PSA values and Gleason scores.
Results: A statistically significant difference was found between the benign and malignant groups in terms of uptake in planar and SPECT images and T/Bg ratios and PSA values. No statistically significant difference was found between uptake patterns of planar and SPECT images and Gleason scores in the malignant group.
Conclusions: SPECT images were superior to planar images in the comparative assessment. Tl-201 SPECT imaging can provide an additional contribution to clinical practice in the diagnosis of prostate cancer and it can be used in selected patients.
How to Cite
Ozyurt, S., Koca, G., Diri, A., Demirel, K., Karakan, T., Resorlu, B., Korkmaz, M., & Germiyanoglu, C. (2015). Evaluation of Tl-201 SPECT imaging findings in prostate cancer. Archivio Italiano Di Urologia E Andrologia, 87(2), 147–150. https://doi.org/10.4081/aiua.2015.2.147
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